báo cáo hóa học: " All-trans retinoic acid induces COX-2 and prostaglandin E2 synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2" potx

... results indicate that ATRA induces activity of the COX-2 promoter and synthesis of COX-2 mRNA and COX-2 protein, resulting in increased PGE 2 production in SH-SY5Y human neuroblastoma cells; and that ... Central Page 1 of 9 (page number not for citation purposes) Journal of Neuroinflammation Open Access Research All-trans retinoic acid induces COX-2...

Ngày tải lên: 19/06/2014, 22:20

... significant inhibition of tumo r growth and reduction in pulmonary and lympha- tic metastasis [200]. Levine’s group reported successful in vivo inhibition of human xenografted glioma, overian, and neuroblastoma ... M, Pernow J: Vitamin C blocks vascular dysfunction and release of interleukin-6 induced by endothelin-1 in humans in vivo. Atherosclerosis 2007, 190:408-4...

Ngày tải lên: 20/06/2014, 03:20

... Using the methodology of Cavrini and associates and Sitoh and colleagues [18,19], an ordinal variable for the EQ-5D index was created by categorizing the continuous variable into 4 levels, and ... Determinants of health-related quality of life in institutionalized older per- sons in northern Sydney. Internal Med J 2005, 35:131-134. 20. Hanninen J, Takala J, Keinanen-Kiukaann...

Ngày tải lên: 18/06/2014, 22:20

... that AFM could be helpful in the design and screening of drugs-modulating protein-protein interaction processes. 1. Introduction A molecular level understanding of protein-protein inter- actions is fundamentall ... affect the interaction force between BSA and rabbit anti-BSA. These findings may enhance our understanding of antigen/antibody binding processes in the presence of...

Ngày tải lên: 20/06/2014, 22:20

... distribution, and reproduction in any medium, provided the original work is properly cited. We study variational-like inclusions involving in nite family of set-valued mappings and their equivalence ... wide class of problems arising in mechanics, optimization, nonlinear programming, economics, finance and applied sciences, and so forth; see, for example 1–7 and references...

Ngày tải lên: 21/06/2014, 07:20

... pathway, insulin signaling and the expression levels of genes related to insulin action, such as insulin receptor sub- strates and adiponectin [8,9], resulting in obesity-related insulin resistance ... fully understood, the inappropriate actions of adiponectin in obesity-linked insulin resistance are described as a ‘vicious cycle’ of adiponectin and insulin resistance [36]. Fo...

Ngày tải lên: 22/03/2014, 21:21

... function of Aurora kinases and therefore no synergism is seen when treating with a combination of both drugs. Tumors that Inhibition of Aurora kinases results in cell deathFigure 3 Inhibition of Aurora ... mitotic spindle checkpoint involving chromosome maturation and segregation [13-15]. Two proteins known to bind and initiate activation of Aurora-A are TPX2 [16,17] and A...

Ngày tải lên: 18/06/2014, 15:20

... cytometry Platelet expression of P-selectin and binding of fibrinogen were measured by flow cytometry as indicators of platelet activation [29-32]. To tubes intended for fibrinogen bind- ing analysis, 10 ... variables con- stituting these factors, which resulted in no intra- Table 1: Binding of fibrinogen and expression of P-selectin as measured by flow cytometry. Type of me...

Ngày tải lên: 18/06/2014, 15:20

... activity of a kinesin inhibitor. Cancer Res 2004, 64:3276-3280. 26. Tao W, South VJ, Diehl RE, Davide JP, Sepp-Lorenzino L, Fraley ME, Arrington KL, Lobell RB: An inhibitor of the kinesin spindle ... Falus A: Autocrine and para- crine regulation by cytokines and growth factors in melanoma. Cytokine 2000, 12:547-554. 33. Nicolini A, Carpi A, Rossi G: Cytokines in breast cancer. Cyt...

Ngày tải lên: 18/06/2014, 15:20

... communicate effectively with the media, including increased understanding of critical research findings to attract or sustain funding and build new profes- sional partnerships that will further ... your field in the local and national media. Often times these people can be found attending major conferences and meetings. Introduc e yourself. Briefly explain what you are working on a...

Ngày tải lên: 18/06/2014, 16:20