... [30,31], and the second iscleavage of the p220 component of the cap-binding pro-tein complex [32], resulting in the shut off of host proteinsynthesis. On the other hand, the function of L of the ... proteins of Theiler's murine encephalomyelitis virus (TMEV) and their regulation of the virus& apos; biological activitiesMasumi Takano-Maruyama, Yoshiro Ohara*, Kunihiko Asakura and Takako ... VP1 and VP2, areimportant for virus persistence and demyelination [1,3].In addition to these structural proteins, two proteins des-ignated leader (L) and L* that are located in the N end of the...