báo cáo hóa học: " Interferon-γ increases neuronal death in response to amyloid-β1-42" pdf
Báo cáo hóa học: "Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-a 2b treatment" pptx
... week of treatment. Although they did not bring about therapyFigure 5 Determination of transforming growth factor-b, interleukin-10 and autoantibody in interferon-a 2b- treated patients with melanoma. (A) ... patients with melanoma (22 patients treated in this study and the other 22 patients who werereferred to our institution during the study); these dataagain suggest that Treg values are higher in patients with ... (Treg) levelsby week in the 22 patients with melanoma treated with interferon-a 2b. (B)Box plot showing circulating regulatory T cell (Treg) levels by week in the 22 patients with melanoma treated...
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báo cáo hóa học: " The microglial "activation" continuum: from innate to adaptive responses" pdf
... of the CD40-CD40 ligand interac-tion. In the context of Aβ challenge, CD40 ligation is able to shift activated microglia from innate to adaptive activa-tion. Further, it seems that the cytokine ... cells [20,21]. On the other hand, inresponse to debris from apoptotic cells, the MΦ mounts aphagocytic response essentially in the absence of pro-inflammatory cytokines [22]. The most likely reason ... peptide. We further assessedputative modulation of microglial Aβ phagocytosis bycytokines known to promote effector T cell function, andfound that the pro-inflammatory Th1-type cytokines IFN-γ...
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báo cáo hóa học: " Interferon-γ increases neuronal death in response to amyloid-β1-42" pdf
... someinflammatory cytokines as risk factors for AD [7] suggest-ing that cytokine production within the brain may influ-ence neuropathogenesis. While the effects of cytokines onastroglial cells within ... containing amino acid residues 82 to 146of the human PrP protein (HuPrP82-146) corresponding to a PrP fragment found in certain prion-infected humanbrains [10], a control peptide containing ... IFN-γ increases prostaglandin E2 production in response to amyloid-β or HuPrP82-146. SH-SY5Y neuroblastoma cells were pre-treated for 24 hours with 1 ng/ml cytokines as shown prior to the...
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báo cáo hóa học: " Wallerian degeneration: the innate-immune response to traumatic nerve injury" potx
... 14REVIE W Open Access Wallerian degeneration: the innate-immune response to traumatic nerve injuryShlomo RotshenkerAbstract Traumatic injury to peripheral nerves results in the loss of neural ... Further, cytokinesmay be divided into major classes. Inflammatory cytokines(e.g. TNFa,IL-1a,andIL-1b; also referred to as pro-inflammatory) promote the production of inflammatorymediators, ... depends on the ensemble of cellularand m olecular events that develop distal to lesion sitesall the way towards denervated targ et tissues. Thoserepresent the PNS response to traumatic nerve injuryand...
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báo cáo hóa học: " Proinflammatory and proapoptotic markers in relation to mono and di-cations in plasma of autistic patients from Saudi Arabia" docx
... caspase3as a proapoptotic marker, IL6 and TNFa as proinflamma-tion markers in the plasma of autistic patients from Saudi Arabia in an attempt to understand the role and relation- ship of these biochemical ... Ca2+ and K+concentrations in plasma of autistic patients could be easily related to thepostulated increase of brain cytok ines (TNFa and IL6)aft er infiltration from pla sma to brain. Experimental ... proinflammatory cytokines and caspase3 as proapoptotic biom arker were determined in plasma of 25 Saudi autistic male patients and compared to 16 age and gender matching control samples.Results: The obtained...
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báo cáo hóa học:" Adeno-associated virus: from defective virus to effective vector" pdf
... number not for citation purposes)Virology JournalOpen AccessReview Adeno-associated virus: from defective virus to effective vectorManuel AFV Gonçalves*Address: Gene Therapy Section, Department ... by the co-receptors αvβ5 integrin heterodimers[21], fibroblast growth factor receptor type 1 [22] and thehepatocyte growth factor receptor, c-Met [23]. The use ofubiquitous heparan sulphate ... vector: the manip-ulation of AAV virions. Virology 2000, 278:301-308.73. Grimm D, Kay MA: From virus evolution to vector revolution:use of naturally occurring serotypes of adeno-associated virus...
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báo cáo hóa học:"The role of disclosure in relation to assent to participate in HIV-related research among HIV-infected youth: a formative study" docx
... con-servative approach to informing and obtaining assent from children who participated in the operational research, which was approved by all affiliated institu-tional review boards. We obtained ... included as a part of the assent process prior to research participation, a component of research participation, or not incorporated in any aspect of the child's involvement in the research. ... CentralPage 1 of 10(page number not for citation purposes)Journal of the International AIDS SocietyOpen Access Research The role of disclosure in relation to assent to participate in HIV-related...
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báo cáo hóa học:" Prevalence of visual impairment in relation to the number of ophthalmologists in a given area: a nationwide approach" ppt
... purposes)Health and Quality of Life OutcomesOpen AccessResearch Prevalence of visual impairment in relation to the number of ophthalmologists in a given area: a nationwide approachAntoine J Lafuma1, ... Rueil-Malmaison, FranceEmail: Antoine J Lafuma - antoine.lafuma@cemka.fr; Antoine P Brézin - antoine.brezin@cch.ap-hop-paris.fr; Francis L Fagnani - francis.fagnani@cemka.fr; Mounir Mesbah - mesbah@ccr.jussieu.fr; ... activities.According to the International Statistical Classification of Diseases, Injuries and Causes of Death, visual impairment includes both low vision and blindness. Low vision isdefined as visual acuity...
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Báo cáo hóa học: " Research Article Hölder Quasicontinuity in Variable Exponent Sobolev Spaces" pdf
... 5.4.Hindawi Publishing CorporationJournal of Inequalities and ApplicationsVolume 2007, Article ID 32324, 18 pagesdoi:10.1155/2007/32324 Research Article Hölder Quasicontinuity in Variable Exponent ... functions are dense in W1,p(·)(Rn).Instead of approximating by smooth functions, we are interested in Lusin-type ap-proximation of variable exponent Sobolev functions. By a Lusin-ty pe approximation ... the original func-tion at every point. In particular, our result implies that every variable exponent Sobolev function can be approximated in the Lusin sense by H¨older continuous Sobolev...
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Báo cáo sinh học: "Metabolic reconfiguration is a regulated response to oxidative stress" pdf
... orfollowing exposure to radical-generating compounds. ROScause wide-ranging damage to macromolecules, which caneventually lead to cell death and thus to aging and a rangeof diseases [1]. To protect ... themselves against this damage,cells have effective defense mechanisms, including anti-oxidant enzymes and free radical scavengers [2]. It is nowwell established that most cells can adapt to oxidative ... generatingNADPH.AAbbssttrraacctt A new study reveals that, in response to oxidative stress, organisms can redirect theirmetabolic flux from glycolysis to the pentose phosphate pathway, the pathway...
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Báo cáo khoa học: "The behavior of oaks in response to natural and induced exposure to the surfactant ABS" potx
... alt="" Original article The behavior of oaks in response to natural and induced exposure to the surfactant ABSS MoriccaE PaolettiC Comparini21Istituto di Patologia e ... could increase the tolerance of succeeding generations of trees by selecting for pollen grains thatare surfactant- tolerant. The alterations in the leaf waxes and in the pollen ... effect of the surfactant on the leaf wax structure. Though all species were affected, they dif-fered in their tolerance to ABS. The effect of ABS was also tested on the...
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Báo cáo y học: "volution of an adenocarcinoma in response to selection by targeted kinase inhibitors" potx
... Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biology 201011:R82.Submit your next manuscript to BioMed Centraland take full advantage of: • Convenient ... presence in the tonguemay indicate an origin in a minor salivary gland. Adeno-carcinomas of the tongue are rare and represent theminority (20 to 25%) of the salivary gland tumors affect-ing the tongue ... loss of heterozygosity; MAPK: mitogen-activated protein kinase; mTOR: mammalian target of rapamycin; PET-CT: positron emissiontomography-computed tomography; PI3K: phosphoinositide 3 -kinase; ...
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báo cáo khoa học: " Analysis of gene expression in response to water deficit of chickpea (Cicer arietinum L.) varieties differing in drought tolerance" pps
... 10:24http://www.biomedcentral.com/1471-2229/10/24Page 12 of 14RESEA R C H ARTIC L E Open Access Analysis of gene expression in response to water deficit of chickpea (Cicer arietinum L.) varieties differing in drought toleranceDeepti Jain, Debasis ... gene expression in response to water deficit of chickpea (Cicer arietinum L.) varieties differing in drought tolerance. BMC Plant Biology 2010 10:24.Submit your next manuscript to BioMed Centraland ... stress-mediated gene expression in chickpea have beenreported. In this study we described an analysis of gene expression in chickpea in response to drought stress andintended to carry out a...
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Báo cáo khoa học: " Endocrine and Ovarian Changes in Response to the Ram Effect in Medroxyprogesterone Acetate-primed Corriedale Ewes" ppsx
... Forsberg M: Endocrine and ovarian changes in response to the ram effect in medroxyprogesterone acetate-primed corriedale ewes during the breeding and nonbreeding-season. Acta vet. scand. 2005, 46, ... gonadotrophin, ram stimulus, teaser rams, ewe.Acta vet. scand. 2005, 46, 33-44.Acta vet. scand. vol. 46 no. 1-2, 2005 Endocrine and Ovarian Changes in Response to the Ram Effect in Medroxyprogesterone ... anestrus; and (c) the endocrine pattern of the in- duced follicular phase, which is related to the depth of anestrus, may be reflected in the behavioral responses to MAP priming and the ram effect. anestrous...
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Báo cáo y học: "Genome-wide gene expression in response to" pps
... peptidase, trypsin-likeserine and cysteine proteases (12 genes), as well as proteinswith putative α2-macroglobulin domains (three genes), whichmay be involved in protease inhibition. These genes ... GO:00096132333127834511111211363211221223591333Molting cycle/ pupHemocyanin, N-terminal/C-terminalIAlpha-2-macrog lobu li nITrypsin-like serine & cysteine proteaseIEnzym e re gu l ato r activityGO:0030234Proteolys peptidolysResp ... genes in our study appeared in one or more of the lists of genes identified as being involved in immunity in the microbial pathogen studies in adults, andonly 8-10% of the genes in our study were...
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