báo cáo hóa học: " Interleukin-1 mediates Alzheimer and Lewy body pathologies" potx

... purposes) Journal of Translational Medicine Open Access Research Semi-allogeneic vaccines and tumor-induced immune tolerance Jin Yu 1 , Mark S Kindy 1,3,4 and Sebastiano Gattoni-Celli* 2,3,4 Address: 1 Department ... APC and a Th-1-type immune response, semi-allo- geneic vaccines also inhibit tumor-induced immune tolerance and anergy. Methods Cells and semi-alloge...

Ngày tải lên: 18/06/2014, 15:20

... We hypothesize some biological effects of ginseng are due to its anti-inflammatory effects. Methods: Human promonocytic U937 cells were used to investigate the immunomodulatory effects of ginseng ... Access Research Bioactivity-guided identification and cell signaling technology to delineate the immunomodulatory effects of Panax ginseng...

Ngày tải lên: 18/06/2014, 15:20

... 17 (page number not for citation purposes) Journal of Translational Medicine Open Access Review Institutional shared resources and translational cancer research Paolo De Paoli Address: Centro di ... of the shared resources necessary to support research activities in a com- prehensive cancer center. Aims and advantages of estab- lishing efficient shared resources for...

Ngày tải lên: 18/06/2014, 15:20

... focused on investigating genes and pathways involved in viral carcinogenesis and pro- gression to HCC in HCV-chronically infected patients. Materials and methods Patient and Tissue Samples Liver ... of genes upregulated IPA image. BioMed Central Page 1 of 14 (page number not for citation purposes) Journal of Translational Medicine Open Access Research Gene profiling, biomarker...

Ngày tải lên: 18/06/2014, 15:20

... and interpretation, manuscript writing; GMH: collection and/ or assembly of data, data analysis and interpretation, manuscript writing; CA: collection and/ or assembly of data, data analysis and ... collection and/ or assembly of data, data analysis and interpretation, manuscript writing; AR: con- ception and design of the study, experimental subject, col- lection and/ or assem...

Ngày tải lên: 18/06/2014, 15:20

... number not for citation purposes) Journal of Translational Medicine Open Access Review Human immunodeficiency virus and human papilloma virus - why HPV-induced lesions do not spontaneously resolve ... Prevalence and risk fac- tors for human papillomavirus infection of the anal canal in human immunodeficiency virus (HIV)-positive and HIV-neg- ative...

Ngày tải lên: 18/06/2014, 15:20

... directly augmenting proliferation of stem cells. The combination of LLL together with allogeneic and autolo- gous stem cells, as well as post-mobilization directing of stem cells will be discussed. Introduction ... mononuclear cells, a heterogeneou s population of T cells, B cells, NK cells, and monocytes has been described to induce chro- matin relaxation and to augment...

Ngày tải lên: 18/06/2014, 16:20

... EDI T O R I A L Open Access Cell and gene therapies: moving from research to clinic David F Stroncek 1* , Raj K Puri 2 Editorial Cell and gene therapy clinical trials began ... Artificial antigen presenting cells are being made by introducing costimulatory mole- cules into cell lines and these cells are being used to expand cytotoxic T cells in vitro. Regenerat...

Ngày tải lên: 18/06/2014, 16:20

... al.: Ezrin promotes invasion and metastasis of pancreatic cancer cells. Journal of Translational Medicine 2010 8:61. Submit your next manuscript to BioMed Central and take full advantage of: • ... of 14 RESEA R C H Open Access Ezrin promotes invasion and metastasis of pancreatic cancer cells Yunxiao Meng, Zhaohui Lu, Shuangni Yu, Qiang Zhang, Yihui Ma,...

Ngày tải lên: 18/06/2014, 16:20

... Access Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice Claudia Raja Gabaglia 1 , Alexandra ... combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induc...

Ngày tải lên: 18/06/2014, 16:20

... sig- naling enzymes and transcription factors. Zinc is required for the activity of more than 300 enzymes, interacting with zinc- binding domains such as zinc fin- gers, RING fingers, and LIM domains ... The RING finger domain is a zinc finger which contains a Cys3HisCys4 amino acid motif, binding two zincs, con- tains from 40 to 60 amino acids. RING is an acronym specifying Really...

Ngày tải lên: 18/06/2014, 16:20

... Bonanno et al.: Thymoglobulin, interferon-g and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures. Journal of Translational Medicine 2010 8:129. Submit ... interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures Giuseppina Bonanno 1,2 , Paola Iudicone 2 , Andrea Ma...

Ngày tải lên: 18/06/2014, 16:20

... neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia. In contrast to in vitro studies, post mortem data do not support a causal relation between the activation ... colocalization of COX-2 with ppRb in neurons in the temporal cortex of AD and control cases [6]. Increased neuronal COX-2 e...

Ngày tải lên: 19/06/2014, 22:20

... Neuroinflammation Open Access Research Interleukin-1 mediates Alzheimer and Lewy body pathologies W Sue T Griffin* 1,3,4,5 , Ling Liu 1 , Yuekui Li 1 , Robert E Mrak 2,3 and Steven W Barger 1,3,4 Address: ... Abstract Background: Clinical and neuropathological overlap between Alzheimer& apos;s (AD) and Parkinson's disease (PD) is now well recognized. Such cases of c...

Ngày tải lên: 19/06/2014, 22:20