báo cáo hóa học: " Peripheral reductive capacity is associated with cognitive performance and survival in Alzheimer''''''''s disease" potx
báo cáo hóa học: " Peripheral reductive capacity is associated with cognitive performance and survival in Alzheimer''''s disease" potx
... competing inter-ests.Cumulative survival of patients with Alzheimer's disease with low (solid line) and high (dashed line) initial AOC levelsFigure 2Cumulative survival of patients with ... also consistent with the finding of lower oxida-tive resistance of plasma and CSF from AD patients com-pared with controls [18]. These findings further indicatethat oxidative stress is a pervasive ... evaluates thetotal reductive capacity present in serum, are decreased in AD and are positively associated with the survival ofpatients. The AOC levels were associated with cognitive scores, but...
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báo cáo hóa học: " Using animal models to determine the significance of complement activation in Alzheimer''''s disease" pptx
... deposition of APP is widespread in the brain,including the cortex and hippocampus. Phosphorylatedtau immunoreactivity is present in neurons and glia in thecortex and hippocampus, and intracellular ... numerous regulatory proteins including CD59, clus-terin, vitronectin, C1-inhibitor, C4-binding protein,decay-activating factor, and Factor H, which inhibit differ-ent steps in the complement cascade. ... activationTAPP and 3xTg-AD miceMutations in the gene encoding for human tau proteinhave been linked to the development of frontotemporaldementia with parkinsonism [115]. By combining thismutation with...
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báo cáo hóa học:" A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study" pdf
... thesefindings. The relative risks for poor outcome of the twopolymorphisms and combination of both were 1.6, 1.84 and 1.80. This effect size was in line with the data pub-lished by Baugh and ... allele with tuberculosis and (ii) of the -173 C allele in combination with the -794 CATT7 microsatellite with severe malarial anemia, respectively [34,35]. These find-ings seem to be in line with ... forTable 1: Baseline characteristics of patients with severe sepsis and patients with abdominal surgery without signs of infection or inflammation (* unpaired t test, ** Fisher's exact...
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báo cáo hóa học:" Reduced renal function is associated with progression to AIDS but not with overall mortality in HIV-infected kenyan adults not initially requiring combination antiretroviral therapy" potx
... details1Division of Infectious Diseases, Indiana University School of Medicine,Indianapolis, IN, USA.2Moi University School of Medicine, Eldoret, Kenya.3Division of Biostatistics, Indiana University ... with the dataanalysis, assisted in interpretation of the results and provided final approvalof the manuscript. MG assisted in interpretation of the results and providedfinal approval of the ... results and provided final approval of the manuscript.CS performed the data analysis, assisted in interpretation of the results and provided final approval of the manuscript. BM assisted with the...
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báo cáo hóa học: "Effect of step-synchronized vibration stimulation of soles on gait in Parkinson''''s disease: a pilot study" doc
... left and right legs in the stride interval and its corre-sponding CV.Parkinson's disease groupFigure 2 shows an example of the stride intervals meas-ured during walking with and without ... decreased in thecontrol group. Stride variability, which is an importantmeasure of motor performance and gait unsteadiness, is increased in subjects with a history of falls [19-23] and is an independent ... dopamine defi-ciency in the basal ganglia that results in characteristicmotor abnormalities including postural instability and gait impairment. Short shuffling steps, slow walkingspeed, and increased...
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báo cáo hóa học: " Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors" ppt
... polymorphisms in the genes encoding IL-1α and IL-1β are also associated with increased AD risk. Specifically, variations in the promoter region of IL1A and in the coding region of IL1B influence ... Eldik LJ, Griffin WS: In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis. Neurobiol Aging 1996, 17:761-766. ... hemispheres were collected for protein and mRNA isolation. For histological study, brain tissues were fixed in 10% formalin, embedded in paraffin, sectioned at 7 µm, and prepared for immunohistochemical...
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báo cáo hóa học:" Bcl-2 expression is altered with ovarian tumor progression: an immunohistochemical evaluation" pptx
... sta-tistical analysis of Bcl-2 staining in normal, benign, and cancerous tissue samples. Fisher's exact test was used totest for associations in extent of epithelial and stromalstaining ... transformation and drug-resistant disease, resulting in poorclinical outcome. Likewise, studies indicate improved clinical outcome with increased presence oflymphocytes. Therefore, we sought to examine ... pathology between 2000 and 2001. All tissue specimens were fixed with 10% for-malin and paraffin-embedded. Four micron sections werestained with haematoxylin and eosin (H & E) and theslides were...
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Báo cáo hóa học: "Early detection of urothelial premalignant lesions using hexaminolevulinate fluorescence cystoscopy in high risk patients" potx
... con-comitant or single DYS is associated with a considerablerisk for disease progression [20-22]. However, diagnosis is very difficult because, in the early stages, both lesionsare indistinguisha ble ... Healthcare, Buckinghamshire, United Kingdom) dissolved in 50 ml of solvent to obtain an 8 mmol/L solution was instilled intravesically with a 12 Fr catheter into an emptybladder and left for 90 minutes. ... safely administered intravesically and make these flatlesions visible within an otherwise normal bladdermucosa. Our results confirm the advantage in the diag-nosis of potentially evolving flat...
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báo cáo hóa học: " Assessing the empirical validity of alternative multi-attribute utility measures in the maternity context" potx
... population in England. In so doing, we aim to provide evidence on therelative merits of two prominent multi-attribute utilitymeasures for those involved in analysing and interpretingeconomic ... investigation and took the pri-mary role in analysing the data and drafting the paper. JM and HS were the principal clinical investigators for theoriginal postnatal support workers trial and contributedto ... [SD],median, inter-quartile range, minimum, maximum, 95% and 99% confidence intervals [CIs]) for the EQ-5D and SF-6D utility scores were computed. The within-individ-ual difference in mean utility...
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Báo cáo hóa học: " Autonomous indoor wayfinding for individuals with cognitive impairments" pptx
... analysis, and statisticalanalysis. TYW participated in the field work and coordination of the fieldstudy and assisted with drafting the manuscript. SFC assisted with recruitingparticipants with cognitive ... challenge to individuals with cognitive impairments in wayfinding is how to remain oriented, recallroutines, and trave l in unfamiliar areas in a way relying on limited cognitive capacity. While ... Allen G: Spatial abilities, cognitive maps, and wayfinding: bases forindividual differences in spatial cognition and behavior. In Wayfindingbehavior: cognitive mapping and other spatial processes....
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