báo cáo hóa học: " A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices" potx
báo cáo hóa học: " A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices" potx
... purposes) Journal of Neuroinflammation Open Access Research A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices Jari Huuskonen* 1 , ... induction at 4 DIV. As a proinflammatory stimulus we used trichostatin A (TSA, 20 nM), a well characterised histone deacetylase inhibitor [25] a...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: "A Dynamic Neuro-Fuzzy Model Providing Bio-State Estimation and Prognosis Prediction for Wearable Intelligent Assistants" pptx
... that are unique to this model. Once the model structure and parameters are set, simula- tions are managed on a separate GUI that enables the cre- ation of input trains, state initialisation, and ... both internal and external factors. Internal factors include developmental growth and the aging process. External factors include trauma causing impairment and/or lifestyle changes. When...
Ngày tải lên: 19/06/2014, 10:20
báo cáo hóa học: " Aspirin-triggered lipoxin A4 attenuates LPSinduced pro-inflammatory responses by inhibiting activation of NF-B and MAPKs in BV-2 microglial cells" pptx
... addition, LPS also activates MAPK pathways which lead to the induction of another transcription factor, AP-1. MAPKs are a group of signaling molecules that appear to play key roles in infiammatory processes ... 5’-GGCAACTCTGTTGAGGAAAG-3’ and 5’ - GGCTCTCGGTAGACGAGA-3’, which amplify the 423 bp product for ALX1/FPR-rs1; and 5’ -GTCAAGAT- CAACAGAAGAAACC-3’ and 5’-GGGCTCTCTCAA- GACTA...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway" doc
... that microglial activation does not always lead to neurodegeneration, as microglia can also generate neuronal growth factors, as well as anti- inflammatory cytokines (M2, “alternatively” activated ... for each total RNA sample, linear amplification and biotin-labeling of total RNA (500 ng) were carried out using the Illumina TotalPrep RNA Amplification Kit (Ambion Applied Biosystems,...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases" ppt
... human IgGandPSAweremixedinthemultiplexassayto accommodate staining of autoAb and PSA binding to distinct seroMAP regions, allowing simultaneous quanti- fication of autoAb plus PSA in one reaction ... to be user-friendly to clinical laboratories, the A+ PSA assay has the potential to aid in the diagnosis and prog- nosis of prostate cancer. Additional material Additional file...
Ngày tải lên: 20/06/2014, 03:20
báo cáo hóa học:" A novel role of HLA class I in the pathology of medulloblastoma" docx
... (HLA -A) , 5'-TATAGTCGACCACCCGGACTCAGAGTCTCCT-3' and 5'-ATATGGATCCATCTCAGTCCCTCACAAGA-3' (HLA- B), 5'-ACCTGTACGCCAACACAGTG-3' and 5'-GCCAT- GCCAATCTCATCTT-3' ... were: 5'-GAGA- CATCTTGGAACTGGAC-3' and 5'-CTCTGAGTGA- GAATCTGAGC-3' (forward and reverse, TAP1), 5'- GTACAACACCCGCCATCAG-3' and 5'-GGACGTAGGG- TAAACGTCAGC-3&a...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx
... potential of bone marrow cells has been tested into hind limb ischemia animal models [12] and several clinical studies are ongoing to evaluate the efficiency of the intra-arterial administration of ... Miyamoto K, Nishigami K, Nagaya N, Akutsu K, Chiku M, Kamei M, Soma T, Miyata S, Higashi M, Tanaka R, Nakatani T, Nonogi H, Take- shita S: Unblinded pilot study of autologous transp...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " A pilot clinical trial testing mutant von HippelLindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma" doc
... thymine to cytosine which led to a substitution in valine to alanine at position 166. Patient 3 had a mutation at nucleotide number 332 resulting in a change from guanine to thymine that led to a substitution ... Itoh K: Study of tumor-infiltrating lymphocytes for adoptive therapy of renal cell carcinoma (RCC) and metastatic melanoma: sequential proliferation of...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot
... M, Medina P, Zamek R, et al: Phase I clinical and pharmacologic study of 13-cis-retinoic acid, interferon alfa, and paclitaxel in patients with prostate cancer and other advanced malignancies. ... approval of the final manuscript. LPM completed analysis and interpretation of quality of life data and approved of the final manuscript. DV contributed to enrollment, interpretation...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Patients with chronic fatigue syndrome performed worse than controls in a controlled repeated exercise study despite a normal oxidative phosphorylation capacity" pdf
... phosphorylation and the remaining complexes of the respiratory chain main- tain the mitochondrial membrane potential [35]. Their mitochondria are only active in apoptosis [36]. In line with the ... and Pain Research Center Amsterdam, Waalstraat 25-31, 1078 BR Amsterdam, The Netherlands Full list of author information is available at the end of the article Vermeulen et al. Journal...
Ngày tải lên: 18/06/2014, 16:20