báo cáo hóa học: " Anti-inflammatory therapy by ibudilast, a phosphodiesterase inhibitor, in demyelination of twitcher, a genetic demyelination model" docx

... elements of Jacobian matrix is expressed in Equa- tion (11). Minimax Approach. The minimax optimization in Equation(8) minimizes the largest value in a set of multi-variable functions. An initial estimate ... Quadratic Programming In a quadratic programming (QP) problem, a multi-vari- able quadratic function is maximized or minimized, sub- ject to a set of linear constra...

Ngày tải lên: 21/06/2014, 01:20

... Ovarian Neoplasm. International Collaborative Ovarian Neoplasm trial 1 and Adjuvant ChemoTherapy In Ovarian Neoplasm trial: two parallel randomized phase III trials of adjuvant chemother- apy in ... EORTC-ACTION collaborators: European Organisation for Research and Treatment of Cancer-Adju- vant ChemoTherapy in Ovarian Neoplasm. Impact of adju- vant chemotherapy and surgical stagi...

Ngày tải lên: 18/06/2014, 15:20

... (%) Averaged Active Time (min) Averaged Active Time (min) ±20% Margin ±1.96 SD Mean Table 3: Agreement and difference between estimates and measure of active time. Inside 20% Critical Margin of Agreement ... between the amount of therapy and functional recovery in post-acute rehabilitation care. To this day, only the total time of therapy has been investigated as a potential d...

Ngày tải lên: 19/06/2014, 08:20

... 0.9 hrs, an elimination phase half-life of 3.9 hrs and a terminal elimination half-life of 22.9 hrs [15]. Implications of the hypothesis Antidoping laws exist to provide a safe and fair environ- ment ... regard, phar- macokinetic characteristics, easy availability through the chemical industry and low costs would make cobalt administration the ideal surrogate or complement for rHuEp...

Ngày tải lên: 20/06/2014, 00:20

... Maneekarn N, Morita K, Tanaka M, Igarashi A, Usawattanakul W, Sirisanthana V, Innis BL, Sittisombut N, Nisalak A, Nimmanitya S: Applications of polymerase chain reaction for identification of dengue ... Guzman MG, Kouri G: Advances in dengue diagnosis. Clin Diagn Lab Immunol 1996, 3:621-627. 9. Yamada K, Nawa M, Takasaki T, Yaba S, Kurane I: Laboratory diag- nosis of dengue virus in...

Ngày tải lên: 20/06/2014, 01:20

... markers of liver and kidney and the histological examination of hematoxylin and eosin stained major organs (Figure 5). Taking all these data into consideration, it appears t hat combina- tion therapy ... of infection; ELISA: enzyme-linked immunosorbant assay; TUNEL: terminal deoxynecleotidyl transferase- mediated dUTP nick-end labeling; ALT: alanine transaminase; AST: aspartate aminot...

Ngày tải lên: 20/06/2014, 03:20

... Hasegawa H, Saikawa Y, Suda K, Ando T, Kumagai K, Irino T, Yoshikawa T, Matsuda S, Kitajima M, Kitagawa Y: Clinical significance of circulating tumor cells in blood from patients with gastrointestinal ... with gastrointestinal cancers. Ann Surg Oncol 2008, 15:3092-100. 10. Pachmann K, Camara O, Kavallaris A, Krauspe S, Malarski N, Gajda M, Kroll T, Jörke C, Hammer U, Altendorf-Hofmann A...

Ngày tải lên: 20/06/2014, 03:20

... I A L Open Access Combination therapy: the next opportunity and challenge of medicine Paolo A Ascierto 1* and Francesco M Marincola 2 Abstract From an historical point of view, combination therapy ... as licensable combination therapy. For all the above reasons, we are creating a subsection of the Journal of Translational Medicine dedicated to combi- nation strategies as a...

Ngày tải lên: 20/06/2014, 04:20

... proposed as a mechan- ism of improving follicular and oocyte de velopment [50]. Additionally, the findings of Palomba et al. demonstrate a significant effect of metformin on intrafollicular insulin growth ... et al, Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest. 108, 1167–1174 (2001) 24. IP Salt, G Johnson, SJ Ashcroft, DG Hardie, AMP-act...

Ngày tải lên: 20/06/2014, 07:20