... immunohistochemistry and ELISAs,and guided or performed image analysis, analyzed dataand drafted the manuscript. LJ performed tissue prepara-tion, immunohistochemistry, image analysisand ELISAs.KT ... studies, Aβ1 –40, Aβ1 –42, Aβ1 –15 and dAβ1–15, were synthesized by the BiopolymerLaboratory, Center for Neurologic Diseases (Boston, MA). Aβ1 –15 peptide is a single copy of the first 15 amino acids of ... tissue was harvested, immunohistochemistry performed and computer assisted quantification completed. J20 APP-tg mice primed with an injection of Aβ1 –40/42 and boosted with Aβ1 –40/42 or dAβ1–15...