báo cáo hóa học: " Vascular consequences of passive Aβ immunization for Alzheimer''''''''s disease Is avoidance of "malactivation" of microglia enough?" docx

... Access Commentary Vascular consequences of passive Aβ immunization for Alzheimer's disease. Is avoidance of "malactivation" of microglia enough? Steven W Barger* 1,2,3 Address: 1 Department of ... [19] – and a vascular accumu- lation of CD45 + cells presumed to be microglia. The exper- imental paradigm was one of passive immunization of...

Ngày tải lên: 19/06/2014, 22:20

Ngày tải lên: 19/06/2014, 22:20

... contributions PKG Acquisition of data and writing of manuscript. SP inclusion of patients, grant PI and clinical scoring. CA Acquisition of data. NKS Statistical analysis. AA Interpretation and analysis of data, ... test analysis showed that mean age differ significantly among the groups (p = 0.004). ‡ Duration of disease is the interval between appearance of first symptom...

Ngày tải lên: 19/06/2014, 22:20

... monitoring allows for evaluation of disease progression [4], and VL testi ng can increase adherence and facilitate timely switching of failing regimens, minimizing the development of resis- tance [5]. ... jane.greig@london.msf.org 1 Manson Unit, Médecins Sans Frontières, London, UK Full list of author information is available at the end of the article Greig et al. Journal of...

Ngày tải lên: 20/06/2014, 08:20

... however similar for the detection of pleural plaques and CT was superior for the detection of pleural calcification which is a marker of benign disease. PET can help distinguish between malignant ... highly effective for patients with pleural disease due to other causes. This has not, however, been formally studied for asbestos-related DPT. Conclusion DPT is now a well r...

Ngày tải lên: 20/06/2014, 00:20

... case of the SDQ and by adolescents in the case of socio-demograph- ical variables, Oslo Scale, and presence of a chronic condi- tion. Statistical analysis Descriptive statistics of the Spanish ... cut-off points for groups with more impaired HRQL. Generally, the selection is made in terms of the distribution deciding which proportion of the population would be in the group of...

Ngày tải lên: 18/06/2014, 18:20

... the VE a nd with the use of keyboard for movement. This was accom- plished with a n initial period of experimenter instruc- tion, followed by a period of free exploration of a VE using the keyboard. ... topographi- cal information are, respectively, named “survey” and * Correspondence: marialuisa.rusconi@unibg.it 1 Department of Human Science, University of Bergamo, Bergamo, Ita...

Ngày tải lên: 19/06/2014, 08:20

... immunohistochemistry and ELISAs, and guided or performed image analysis, analyzed data and drafted the manuscript. LJ performed tissue prepara- tion, immunohistochemistry, image analysisand ELISAs. KT ... studies, Aβ1 –40, Aβ1 –42, Aβ1 – 15 and dAβ1–15, were synthesized by the Biopolymer Laboratory, Center for Neurologic Diseases (Boston, MA). Aβ1 –15 peptide is a single copy of the...

Ngày tải lên: 19/06/2014, 22:20

... [20,21]. This may, in part, be related to the formation of anti-interferon beta neutraliz- ing antibodies [22]. In an effort to address this issue, in terms of a marker of response, levels of interferon ... measurement of sHLA in CSF would be most likely to reflect CNS disease activity. Measure- ment of such a biological marker of disease activity could potentially serve as...

Ngày tải lên: 19/06/2014, 22:20

... majority of studies focus on the effects of air pollution in cardiovascular and pulmonary disease [12], accumulating evidence now points to a new role for air pollution in CNS disease [10]. For example, human ... multiplication analysis in Italian familial Parkinson disease. Parkinsonism Relat Disord 2010, 16:228-231. 40. Chiba-Falek O, Lopez GJ, Nussbaum RL: Levels of alpha-sy...

Ngày tải lên: 19/06/2014, 22:20