báo cáo hóa học: " β-Amyloid promotes accumulation of lipid peroxides by inhibiting CD36-mediated clearance of oxidized lipoproteins" pot

... 1 of 12 (page number not for citation purposes) Journal of Neuroinflammation Open Access Research β-Amyloid promotes accumulation of lipid peroxides by inhibiting CD36-mediated clearance of oxidized ... protein, thereby reducing cell surface expression of this oxLDL receptor. Conclusions: Together, these data demonstrate that in the presence of β-amyloid, CD3...

Ngày tải lên: 19/06/2014, 22:20

... invasion ability of MiaPaCa-2 cells Cell motility ability was examined by dete rmining of the migration rate through a polyethylene filter in the absence of Matrigel. The migration rate of the Mia ez22 ... metastatic potential of MiaPaCa-2 cells. These observations might be explained by the fact that MiaPaCa-2 cells is a cell line with low metastatic potential; therefore, the ef...

Ngày tải lên: 18/06/2014, 16:20

... atomic resolution structures of the molecu- lar packing of peptides in amyloid-like structures are beginning to emerge [19], much of our understanding of the structure of amyloid-like fibrils comes ... molecular structures Because of the +5 charge on monomeric glucagon mol- ecules at acidic pH, shielding of charges by anions can increase the rate of fibril formation by relie...

Ngày tải lên: 23/03/2014, 03:20

... metastatic potential of gastric cancer. Int J Cancer 2002, 100:486-90. 20. Shweiki D, Neeman M, Itin A, Keshet E: Induction of vascular endothelial growth factor expression by hypoxia and by glu- cose ... 18 th hour of incubation of monolayer- and 3D-spheroid-cultured CT26 cells. For both culture conditions, the concentration of VEGF was expressed as a function of the total n...

Ngày tải lên: 18/06/2014, 15:20

... values; outliers are marked by aster- isks). Estimation of the performance of classification of breast can-cer samplesFigure 1 Estimation of the performance of classification of breast cancer samples. ... built of 15 spectral components (these were representative of ROC curves Estimation of differences of serum proteome patterns between sub-groups of breast cancers pa...

Ngày tải lên: 18/06/2014, 15:20

... unveiling of cryptic epitopes following inter- nalization of CD4 in complex with gp120 was proposed to explain the pathogenesis of this phenomenon [14,15]. A further in vivo proof of principle of the ... formation of autoreactive CD8 T cells. Apoptosis is an ordered state of cell death in which the structural components of the cell are carefully disassembled by the activity...

Ngày tải lên: 18/06/2014, 15:20

... SNPs of TLR9 and MTCT of HIV-1, revealing that the TLR9 [A;A] and [G;G] haplotypes are associated with a significantly increased risk of MTCT of HIV-1. Genetic variations of TLR9, as a key gene of ... HIV- 1-uninfected, the infection was confirmed by disease onset and/or persistence of HIV-1 antibody after 18 months of age, while lack of infection was confirmed by the lo...

Ngày tải lên: 18/06/2014, 16:20

... systemic treatment due to its potential toxicity. The ability to deliver RU486 systemically and influence the local effects of IL-12 could limit some of the toxic effects of IL-12 and offer a general strategy ... administration of RU486 IP for 1 week. At the end of treatment, TSLN were isolated and analyzed by flow cytometry for their content of Ly49C + NK cells. A representativ...

Ngày tải lên: 18/06/2014, 16:20

... from brain tumours often experience a wide range of cognitive impairments that impair their ability to report on their quality of life and symptom burden. The use of proxy ratings by significant ... Arusell R, Buckner J: A prospective study of quality of life in adults with newly diagnosed high-grade gliomas: comparison of patient and caregiver ratings of quality of life. A...

Ngày tải lên: 18/06/2014, 19:20

... wanted to review the role of Type D personality in potential mechanisms of disease as markers of health risks in apparently healthy people. Finally, we sought to describe potential work-related ... <6 points) were considered to be of ‘low quality’. Results Methodological quality of the studies The evaluation of the methodological quality of the 19 studies by the two reviewe...

Ngày tải lên: 18/06/2014, 19:20