báo cáo hóa học: " Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1β production" pdf
Báo cáo khoa học: Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate potx
... 0.05 c – a Acceleration of deacetylation by substrate and substrate ana- logue. b Acceleration of decarbamoylation by substrate analogue. Acceleration of deacetylation and decarbamoylation by substrate analogue ... enzyme concentration at time t,[E] 0 theinitialconcentrationoffreeenzymeand[Ec] 0 the initial concentration of mono-methylcarbamoylated enzyme. Results Location...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: Inhibition of a-synuclein fibrillization by dopamine analogs via reaction with the amino groups of a-synuclein Implication for dopaminergic neurodegeneration pot
... HSQC spectra of the reactions of a-Syn with quinone and DA. (A) Overlay of the 1 H- 15 N HSQC spectra of a-Syn (black) and the reaction product of a-Syn and Q (red). (B) Overlay of the 1 H- 15 N ... and then the reaction mixtures were analyzed by means of SEC. (B) SDS ⁄ PAGE graph of the fractions from SEC separation of the reaction products of a-Syn with Q (up)...
Ngày tải lên: 23/03/2014, 15:20
Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt
... 8. Effects of 2-APB on ATP-dependent phosphorylation and nucleotide binding to the Ca 2+ ATPase. (A) shows the effects of phosphorylation of the SR Ca 2+ ATPase at varying concentrations of [c- 32 P]ATP, ... Mechanism of inhibition of the (Ca 2+ -Mg 2+ )- ATPase by nonylphenol. Biochemistry 29, 3091–3101. 16. Zhong, L. & Inesi, G. (1998) Role of the S3 stalk segment in...
Ngày tải lên: 31/03/2014, 23:20
báo cáo hóa học:" Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation" doc
... rapid depletion of circulating CD19+ B cells and a suggestion of global B cell activation as evi- denced by significant upregulation of CD86 expression on B cells after infusion [14] (JR and RHV, ... major component of T cell help. Ligation of CD40 on DC, for example, induces increased surface expression of costimulatory and MHC molecules, production of proinflammato...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Detection of epithelial apoptosis in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis" pot
... comparison of local levels of Bcl-2 in pouches from UC, FAP patients and controls revealed that they were similar among the groups (p > 0.05). The expression of FADD and Caspase-8 was similar among ... number of experiments. The results of blots are presented as direct comparisons of bands in autoradiographs and quantified by densito- metry using the Gel-Pro Analyzer 3....
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors" docx
... lesions of Woodrum et al. Journal of Translational Medicine 2010, 8:14 http://www.translational-medicine.com/content/8/1/14 Page 17 of 18 Table 2 Distribution of Kidney Lesion Subtype for A/J and ... injection. Vincristine treated groups received 200 μlofa0.075mg/mLsolutionofvincris- tine once per week for four weeks by IP injection. Sunitinib treated groups received 200 μlofa12mg...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032" potx
... between the V600E and V600K mutations. Our preclinical data demonstrating s imilar kinase activity of the V600K and V600E mutations, together with clear evidence of clinical activity of PLX4032 in ... study of PLX4032: Proof of concept for V600E BRAF mutation as a therapeutic target in human cancer. J Clin Oncol (Meeting Abstracts) 2009, 27:9000. 2. Uribe P, Wistuba I, González...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: "Quality of life in Brazilian obese adolescents: effects of a long-term multidisciplinary lifestyle therapy" pdf
... affect. Cognition and response to behavioral weight control. J Con- sult Clin Psychol. 1988, 56(3):433-439. 23. Gorenstein C, Andrade L: Validation of a Portuguese version of the beck depression inventory and ... depression and anxiety after short and long-term multidisciplinary life- style treatment and, consequently, the improvement observed in scores of mean dimensions of...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " Quality of Life as reported by school children and their parents: a cross-sectional survey" docx
... correlations between mother and daughter, mother and son, father and daugh- ter and father and son reports on the ILC and KINDL were significant, but small and similar (range r = 0.25 to 0.31, and ... explored possible cluster effects. The results of an analysis of unconditional random effects showed that only 3.6% of the total variance of the ILC LQ0-28 scores a...
Ngày tải lên: 18/06/2014, 22:20
Báo cáo khoa học: Induction of raft-like domains by a myristoylated NAP-22 peptide and its Tyr mutant potx
... that the ability of peptides to form domains of PtdIns(4,5)P2 is a conse- quence of the combined interactions of the cationic cluster of amino acid residues and the insertion of hydrophobic amino ... seques- tration to the membrane by removing the anionic por- tion of the protein that would repel anionic lipids. The pI of rat NAP-22 is only 4.5. Another indication of the...
Ngày tải lên: 07/03/2014, 17:20