... paromomycin,neomycin, gentamicin, and kanamycin at the A-site of12S rRNA [14]. Thus, the administration of aminoglyco-side s can induce or worsen hearing loss in these subjectscarrying the ... and ~17% in the two white cohorts from United States and Spain[5,32,33]. However, the incidence o f 1555A > G muta-tion in nonsyndromic hearing loss was much lower than in those with aminoglycoside ... Province,China. Based on a clinician review of the medicalrecord, 98 subjects (58 males and 40 females) had a his-tory of exposure to aminoglycosides including gentami-cin, streptomycin and...