... of themicrophthalmia-associated transcriptor factor (MITF),which is considered to be the "master regulator ofmelanocytes" since it seems to be crucial for melanoblastsurvival and ... p14CDKN2A-MDM2-p53 cascade, whose final effectors are the Bax/Bcl-2 proteins, has been implicated in defective apoptoticresponses to genotoxic damage and, thus, to anticanceragents (in most cases, ... Price ER, Takemoto C, Badalian T, Fisher DE: MAPkinase links the transcription factor Microphthalmia to c-Kitsignalling in melanocytes. Nature 1998, 391:298-301.149. Bertolotto C, Abbe P, Hemesath...