... outlined the direction of, and drafted the manuscript. MJH, CCM and KLE refined the search for information, gatheredreferences and generated the tables and figure. MRJ, RMP, LML providedinformation ... immunotherapy trialsmust engender improved survival and quality of life tobecome integrated into the standard of care regime[5,52-54]. The number of slots open for patient accrual to the immunotherapy ... residual disease at the start of vaccine therapy, and concurrent administra-tion of chemotherapeutics [23,24,46-51]. For valid con-clusions to be reached timely about the value of theseapproaches...