... H, Nakagawa R, TakadaI, Iwaki T, Okada Y, Iida M, Cua DJ, Iwakura Y, Yoshimura A: Pivotalrole of cerebral interleukin-17-producing γδT cells in thedelayed phase of ischemic brain injury. Nat ... stroke has become an impor-tant area of research in translational medicine.Cytokines and brain inflammationCytokines are a group of small glycoproteins that are pro-duced in response to an ... directcell damage, regional brain I/R induces an inflammatoryresponse involving complement activation and genera-tion of active fragments such as C 3a and C 5a anaphylatox-ins. Expression of C 3a and...