Báo cáo sinh học: "Packaging of actin into Ebola virus VLPs" potx

... that actin is indeed packaged into Ebola virus VLPs. Co-expression of a membrane-anchored form of GP enhances release of actin and VP40 by equivalent levels in VLPs. The mucin-like domain of GP ... Black Creek Canal Virus, fowlpox virus, West Nile virus, equine infectious anemia virus, and respiratory syncytial virus RSV [9,10,14,18,20,23,24]. Cellular actin has been...

Ngày tải lên: 19/06/2014, 08:20

... sought to determine whether actin is incorporated into Ebola VLPs, and thus may play a role in assembly and/or budding of Ebola virus. Our results indicated that actin and Ebola virus VP40 strongly co- localized ... cellular actin, and that actin may play a role in assembly and/or budding of Ebola VLPs. Introduction Ebola virus VP40 is known to bud from cells as a...

Ngày tải lên: 20/06/2014, 04:20

... the proteosomal degradation of inhibi- tor of kappa B (IκB) [14]. This results in inhibition of NFκB activity and the NFκB-dependent expression of anti- apoptotic genes of the Bcl-2 family [15]. ... apoptosis of the infected cell. This would go against the plan of survival of productively infected cells followed by retroviruses and so nicely exemplified by HIV Subcellular loca...

Ngày tải lên: 18/06/2014, 18:20

... due to: (1) slowing of the repli- cation process of the infected cells or from production of an inhibitor in situ; or (2) lysis of infected cells causing destruction of the virus and its RNA, ... culturing of the virus, the observed stability of the negative-strand inside the cells is understandable. Although the majority of patient samples described above are of type 1b,...

Ngày tải lên: 19/06/2014, 08:20

... characterization. The very high homology of the nucleotide sequence of the clone with that of the antisense strand of ceruloplasmin suggested that it was the product of a wrong cloning strategy. Nonetheless, it ... translated primary structure of the clone contained a short segment (62–99) that was highly homologous to segment 6–45 of a number of a-chains of phycocyanins [24...

Ngày tải lên: 07/03/2014, 21:20

... successfully incorporate into the PL. Results Incorporation of exogenously injected ZP1 into quail PL To determine whether ZP1 injected intravenously into a bird was incorporated into the PL of the ovarian ... manner. Incorporation of heterologous ZP1 into quail PL In the next set of experiments, we investigated whether there is species specificity in the incorporation of s...

Ngày tải lên: 23/03/2014, 07:20

... survey. Results Observation of routine activities of FWAs Data of 1995 and 1996 showed a consistent pattern of adherence to the recommended protocol for administra- tion of injectables (Table 1). The skills of the ... withdrawal of the interventions. The high coverage of routine activities of the FWAs, such as record- keeping and screening of contraceptive methods, was als...

Ngày tải lên: 18/06/2014, 17:20

... Suitability of the setting and venue of the project to the activities • Extent of utilization of requested equipments • Proficiency of the management team According to the used criteria of assessment, ... achievement of any progress is not dependent on a single professional category of people but it is a joint effort of all categories of workers in the medical sector. Slig...

Ngày tải lên: 18/06/2014, 17:20

... the likelihood of desired health out- comes and are consistent with current professional knowledge. Process indicators of quality of tuberculosis control entail the assessment of what the health ... 2008 25. Awofeso N: Inventory of skin smear practices in 6 Leprosy Control programmes in Nigeria. Leprosy Review 1993, 64(2):150-56. 26. Awofeso N: Appraisal of the knowledge and attit...

Ngày tải lên: 18/06/2014, 17:20

... and management of higher-education courses of good quality, including professional develop- ment courses, that will contribute to enhancing the teach- ing and learning experience of students in ... academic quality of courses and ensure that courses remain relevant in the light of developing knowledge in the discipline. We stress the importance of having clear procedures for appro...

Ngày tải lên: 18/06/2014, 17:20