Báo cáo sinh học: "Importance of disulphide bonds for vaccinia virus L1R protein function" pot

... membrane of the ERGIC, the bonds are isomer- BioMed Central Page 1 of 5 (page number not for citation purposes) Virology Journal Open Access Short report Importance of disulphide bonds for vaccinia virus ... encoded protein disulphide isomerase is required for proper disulphide pairing in active L1R. It is conceiva- ble that cyteine-57 forms an incorrect disulphi...

Ngày tải lên: 19/06/2014, 08:20

... (pfu/ml) pL1 R C34 /4 9S C34 / 57S C34/116S C34 / 136 S C3 4/ 15 8S C49 / 57S C49/116S C49 / 136 S C4 9/ 158 S C 57/ 11 6S C57/ 1 36S C57 / 158S C 11 6/ 136 S C 1 16/ 15 8S C136/ 1 58S 1.0×10 4 1.0×10 5 1.0×10 6 1.0×10 7 1.0×10 8 Virus Titer (pfu/ml) A) B) C) BioMed Central Page 1 of 5 (page number not for citation purposes) Virology Journal Open Access Short report Importance of dis...

Ngày tải lên: 20/06/2014, 04:20

... reflective of a widespread lack of information technology and telecommunications across the African region: a 2004 study conducted by the WHO Regional Office for Africa showed that 22% of health workforce ... pursuit of health workforce development objectives requires sound information and evidence. Against the backdrop of increasing demand for information, building knowledge an...

Ngày tải lên: 18/06/2014, 17:20

... of 13 (page number not for citation purposes) mice much too long (50–70 days) to feasibly screen the efficacy of a large number of potential therapeutics in vivo. Therefore, we passaged the viruses ... Hart MK: Vaccine research efforts for filoviruses. International Journal for Parasitology 2003, 33:583-595. 19. Moe JB, Lambert RD, Lupton HW: Plaque assay for Ebola virus. J Cl...

Ngày tải lên: 18/06/2014, 18:20

... feedback for further research during the study, and approved the final submitted version of this manuscript. Acknowledgments This study was performed within the framework of the Center for Translational ... distributed freely for any purposes (see copyright notice below). For information about publishing your research in EJNMMI Research go to http://www.ejnmmires.com/authors...

Ngày tải lên: 18/06/2014, 18:20

... vaccine development. On the other hand, poxviruses express a wide variety of proteins that are non- essential for virus replication in vitro but help the virus to evade the host response to infection ... may be necessary for rep- lication of some viruses [27,37]. Virulent viruses of SPPV may advocate similar immune evasion mechanisms that deflect down regulation and abortion of...

Ngày tải lên: 18/06/2014, 22:20

... TJ, Saracco G, Bonino F, Crawford K, Marion CD, Crawford KA, et al.: Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV ... 4 Department of Biostatistics, University of Washington, Seattle, WA, USA, 5 Department of Medicine, University of Washington, Seattle, WA, USA, 6 Department of Pediatrics,...

Ngày tải lên: 19/06/2014, 08:20

... virus (TMV) and two potyviruses; Potato virus Y (PVY) and Tobacco etch virus (TEV) potyviruses that infect a large number of plant species. Leaves of N. benthamiana symptomatic for these pathogens ... consisted of 30 cycles of 94°C for 1 min, 58°C for 1 min. and 72°C for 2 mins. JSP001 &JSP002: PCR conditions consisted of 30 cycles of 94°C for 1 min, 45°C for...

Ngày tải lên: 19/06/2014, 08:20

... 8 of 19 (page number not for citation purposes) Effect of 3CD pro (3C pro H40A) on the late stages of poliovirus assembly in vitroFigure 5 Effect of 3CD pro (3C pro H40A) on the late stages of ... the life cycle of poliovirus. These processes include the translation of the input RNA, processing of the polyprotein, formation of membranous replication complexes, uridylylatio...

Ngày tải lên: 19/06/2014, 08:20

... Kinase Acyl- transferase Mvan_2987 Phospho- diesterase RsbW RsbV Hypothetical protein Response regulator Sensor Kinase Mjls_2718 Hypothetical protein RsbW RsbV Response regulator Sensor Kinase Hypothetical protein Mkms_2732 Hypothetical protein RsbW RsbV Signal ... (1997) ELISA for detection of antibody to the E2 protein of GB virus C. J Virol Methods 69, 1–6. Supporti...

Ngày tải lên: 30/03/2014, 02:20