Báo cáo sinh học: " Evidence of HIV exposure and transient seroreactivity in archived HIV-negative severe hemophiliac sera" docx

... fluctuate in intensitywithin many of the archived plasma sets that displayedreactivity (Figure 1 panels 1–3 and Table 2 asterisks). Thegreatest intensity of banding activity in these archived plasma ... of antibodies to HIV HIV-1AB HIV- 1IHIV-2 (rDNA) EIA Archived plasma samples were reassessed for the presence of plasma antibodies reactive with HIV- 1 and/ or HIV- 2antigens using the HIV- 1AB HIV- 1IHIV-2 ... probabil-ity of HIV- 1 exposure from contaminated clotting factorconcentrates [7,47-50].Table 1: Clinical profile and clotting factor concentrate exposure of HIV- Exposed/HIVseronegative hemophiliacs.Hemophilia...

báo cáo hóa học:" Evidence of HIV exposure and transient seroreactivity in archived HIV-negative severe hemophiliac sera" ppt

... CentralPage 1 of 11(page number not for citation purposes)Virology JournalOpen AccessResearch Evidence of HIV exposure and transient seroreactivity in archived HIV- negative severe hemophiliac ... Thegreatest intensity of banding activity in these archived plasma sets coincided with years of highest-risk of expo-sure to HIV contaminated clotting factor concentrate(1980–1985). None of the HIV- 1 ... of antibodies to HIV HIV-1AB HIV- 1IHIV-2 (rDNA) EIA Archived plasma samples were reassessed for the presence of plasma antibodies reactive with HIV- 1 and/ or HIV- 2antigens using the HIV- 1AB HIV- 1IHIV-2...

báo cáo sinh học:" Task-shifting HIV counselling and testing services in Zambia: the role of lay counsellors" pot

... the lay counsellors we inter-viewed were interested in future training and continuing in what was considered a professional field, includingobtaining advanced certificates and degrees. The lay ... contribution of Rebecca Dirks and Dr Justin Mandala of Family Health International, Arlington, Virginia, United States of America, in reviewing the manuscript.They also thank clients, staff and the Ministry ... Counseling and Testing Efficacy Study Group: Counsellors' perspectives onthe experience of providing HIV counselling in Kenya and Tanzania: the voluntary HIV- 1 counselling and testing effi-cacy...

báo cáo sinh học:" Health workforce skill mix and task shifting in low income countries: a review of recent evidence" pptx

... workers being trained in one year in voca-tional schools in Ethiopia, to assistant medical officersbeing trained in obstetrics in Mozambique, to physicianassistants being trained in the United ... sub-stituting tasks among professionals, delegating tasks toprofessionals with less training, including creating a newcadre, delegating tasks to non-professionals, or a co mbi-nation of these ... participated in the acquisition and interpretation of the studies and drafting themanuscript. EA, AS, and MV participated in the study concept and design, and drafting the manuscript. All authors read and...

Báo cáo sinh học: " Role of HIV-1 subtype C envelope V3 to V5 regions in viral entry, coreceptor utilization and replication efficiency in primary T-lymphocytes and monocyte-derived macrophages" docx

... determined and compared to a known syncy-tium-inducing (SI) virus (HIV- 1NL4-3) and a non-syncytium-inducing (NSI) viruses (HIV- 1BaL and HIV- 1Ada-M) by infect-ing the MT-2 cell line with ... coreceptor utilization of sub-type C HIV- 1 could be predominantly R5 even late in infection.Syncytium inducing capacity of subtype C chimerasWe examined the syncytium-inducing ability of the sub-type ... of infectivity whencompared to other chimeras and primary isolate controlsindicating an increased rate of entry for these chimeras.The levels of entry using increasing virus counts (5000and...

Báo cáo sinh học: " Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription" potx

... Phosphorylation of the cAMP responseelement binding protein CREB by cAMP-dependent proteinkinase A and glycogen synthase kinase-3 alters DNA-bindingaffinity, conformation, and increases net ... serine 62, threonine 64 and serine 68 [22]. HIV- 1 Tat is a 14 kDa viral protein involved in the regula-tion of HIV- 1 transcriptional elongation [24-26] and in itspresence, viral replication increases ... pro-tein from entering the nucleus. However, HIV- 1 subtype Cviruses which are rapidly expanding, carry mutations in Tat R57S and G63Q within and close to the basic domain, and yet exhibit increased...

Báo cáo khoa học: Evidence of a new phosphoryl transfer system in nucleotide metabolism doc

... equilibrium towards ADP and inosine synthesis. The proposed mechanism involves the association of adenosine kinase and myokinase through non-covalent, transient interac-tions that induce slight conformational ... simulation. Using the MD trajectory, possiblechanges in AMP position and in the network of bondsbetween the AMP molecules and binding pockets wereexamined. In the case of rat MK, one of the twobound ... network and cooperate in a reaction not reportedpreviously.Keywordsadenosine deaminase; adenosine kinase;adenylate kinase; ADP; ATPCorrespondenceR. Leoncini, Department of InternalMedicine,...

Báo cáo sinh học: " Induction of Th1Immune responses following laser ablation in a murine model of colorectal liver metastase" potx

... tumor and normal liver tissue swere examined. Scoring criteria was used to estimate theamount and intensity of staining seen in each sample.Thegradingsystemusedwas:as:0:nostaining1:faintstaining; ... site of injury and systemic induction of immune responses as discerned by the presence of IFNg secreting splenocytes. LA of livertumors induced significant increase of CD3+ T-cells at site of injury, ... time points following LA and changes in CD3+ T cells and Kupffer cells (F4/80 marker) infiltration and the expression of interferon gamma (IFNg) were investigated byimmunohistochemistry and ELISpot....

Báo cáo sinh học: "Stability of a generalized quadratic functional equation in various spaces: a fixed point alternative approach" pdf

... exists a mapping Q : X → Y satisfying the following:(1) Q is a ﬁxed point of J, i.e.,Q ((2 − c − n)x) = (2 − c − n)2Q(x) (7)for all x ∈ X. The mapping Q is a unique ﬁxed point of J in the setM ... on the space. In particular, Bag and Samanta [53], following Cheng and Mordeson [54], gave an idea of fuzzy norm in such a manner that the corresponding fuzzymetric is of Karmosil and Michalek ... exists a mapping Q : X → Y satisfying the following:(1) Q is a ﬁxed point of J, i.e.,Qx2 − c − n=1(2 − c − n)2Q(x) (10)for all x ∈ X. The mapping Q is a unique ﬁxed point of J in the...

Báo cáo sinh học: " Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein" doc

... locations (amino acids 450,479 and 480) with phenylalanine, arginine and leucine in NiV replaced by tyrosine, lysine and isoleucine in HeV[6,46]. These differences in the sequence of either peptidedid ... containing 1% BSA for 5 min. 40 µl of anti-P antiserum (1:200 in PBS-BSA) was applied toeach well and incubated at 37°C for 30 min. Slides wererinsed with PBS containing 0.05% Tween 20 (PBS-T) and washed ... trimer of the paramyxovi-rus fusion protein: parallels to influenza virus hemagglutinin and HIV- 1 gp41. Virology 1998, 248:20-34.30. Wild TF, Buckland R: Inhibition of measles virus infection and fusion...

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