Báo cáo sinh học: " Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA" pdf
Báo cáo khoa học: Human liver mitochondrial cytochrome P450 2D6 – individual variations and implications in drug metabolism docx
... sequence and the phosphory- lation domains of CYP2B1 and 2E1 were compared with the amino acid sequence of human CYP2D6 (Fig. 3A). The N-terminal amino acid sequence of CYP2D6 bears resemblance to the ... of CYP2D6 in mitochondria and micro- somes, whereas almost all (97–99%) of the CYP2D6 in HL131 and 141 was associated with the microsomal fraction (Fig. 1...
Ngày tải lên: 29/03/2014, 23:20
Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
... analysis, and the determination of released ammonia. The coupled enzyme assay revealed the mechanism of the deamination reaction and the subsequent metabolism, including the deamination step. The product ... absorption spectra of reaction products and the purified enzyme were recorded with a Beckman DU 650 spectrophotometer. Fluorescence spectra of the purified...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt
... part of the synthesis can occur at the surface of the granule. The apparent polarized growth of the granules is consistent with either an aniso- tropic distribution of GBSSI or a filling of the ... of the GBSSI gene in green algae. Establishing the nature of the STA2 locus Two separate lines of evidence show that the cDNA and gDNA clones correspond to t...
Ngày tải lên: 22/02/2014, 07:20
Tài liệu Báo cáo khoa học: "HORN EXTENDED FEATURE STRUCTURES: FAST UNIFICATION WITH NEGATION AND LIMITED DISJUNCTION" ppt
... clauses, we further define the following quantities. L = The length of ~I,; i.e., the sum of the lengths of all literals occurring in 4~. P = The number of distinct terms of the form (or fl) ... be true (ap denotes the concate- ,nation of a and fl), and another term of the form - 36 - (c, : T) occurs as au antecedent of a ilorn feature clause, (w...
Ngày tải lên: 22/02/2014, 10:20
Báo cáo khoa học: High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease pdf
... some of its targets such as thrombin [28]. The co-factor effect of heparin is due to a change in the conformation of the SERPIN as well as the ability of heparin to co-join the protease with the ... activation of FSAP (Fig. S4). Hence, the effect of PolyP was not due to a contaminant. These studies show that the pattern of binding of polyanions to FSAP is ide...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Post-ischemic brain damage: NF-jB dimer heterogeneity as a molecular determinant of neuron vulnerability pdf
... 2004 and 2005, 2006; by the Centre of Study and Research on Aging, Brescia; by MIUR Center of Excellence for Innovative Diagnostics and Therapeutics (IDET) of Brescia University and by the Rotary ... in the cytoplasm by masking the NF-jB nuclear localiza- tion sequence and the DNA- binding domain. Indeed, IjBa leads a constant shuttling of the p50 ⁄ p65 com- ple...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: A novel metallobridged bis(b-cyclodextrin)s fluorescent probe for the determination of glutathione doc
... according to the formula C = KS 0 ⁄ S, where K = 3 (standard devia- tion = 1.36), obtained from a series of 11 reagent blanks, and S is the slope of the standard curve. The relative standard deviation ... experiments. Influence of the concentration of metallobridged bis(b-CD)s 2 The influence of the concentration of 2 on fluorescence intensity is shown in Fig. 4. As c...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Cofactor-independent oxygenation reactions catalyzed by soluble methane monooxygenase at the surface of a modified gold electrode pot
... Fig. 2 and then cycled from 0 to )0.6 V at 2 mVÆs )1 . The arrow shows the effect of increasing catalase concentrations (0, 2.4, 4.8 and 7.2 l M , respectively). The effect of ventilating the reaction ... suggesting that MMOB is controlling the flow of electrons to MMOH as it does in the presence of MMOR and NAD(P)H. Most importantly, in the presence of MMOB and c...
Ngày tải lên: 17/03/2014, 09:20
Báo cáo khoa học: Growth hormone/JAK-STAT axis signal-transduction defect A novel treatable cause of growth failure pdf
... that 69 and 93% of the C and the S fibroblasts, respectively, resided in the G o ⁄ G 1 phase of the cell cycle. Addition of hGH (200 and 1000 ngÆmL )1 ) decreased the percentage of S cells in the ... different doses of hGH increased the percentage of DNA- synthesizing cells with the same kinetics in the C and S cells, albeit the differences between C...
Ngày tải lên: 23/03/2014, 10:21
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... increase in the stability of the quintuple mutant is almost the same as the sum of the three individual stabilities [9,29]. Thus, the mutation(s) in each of the three regions contribute to the overall ... in the wild-type PA c-551 and its quintuple mutant. The mutated residues in the quintuple mutant, and the corresponding ones of the wild-type PA c-551...
Ngày tải lên: 24/03/2014, 03:21