... tailored design of drug candidates. The H1 receptor has an important role in many physiological and pathological processes and a better understanding of its structure and of its ligand interaction ... 184/199 and EU grant BIO4-CT97-2101toH.J.M.DeG.andW.J.DeG.H.J.M.DeG.isa recipient of a PIONIER award of the Chemical council (CW) of the Netherlands Foundation for Scie...
Ngày tải lên: 30/03/2014, 14:20
... created. 4 http://dev.mysql.com 5 http://www.iana.org/assignments/ media-types/ Finally the Command Dispatcher signals the suc- cessful completion of the task back to the Client. Figure 3 shows the class diagram of the master data model. The design is woven around the gen- eral ... sharing them with other users and groups. It follows the look and feel of the Wind...
Ngày tải lên: 31/03/2014, 20:20
Tài liệu Báo cáo khoa học: Secondary substrate binding strongly affects activity and binding affinity of Bacillus subtilis and Aspergillus niger GH11 xylanases docx
... in the present study had an average arabinose ⁄ xylose ratio of 0.60 and the average arabinose ⁄ xylose ratio of the OSX was 0.08, as assessed by hydrolysis of the materials and analysis of the ... of CBMs. Results and Discussion Genetic engineering of the SBS Residues of the SBS of both XBS and XAN involved in substrate interaction were selected based on...
Ngày tải lên: 14/02/2014, 19:20
Báo cáo Y học: High affinity binding between laminin and laminin binding protein of Leishmania is stimulated by zinc and may involve laminin zinc-finger like sequences doc
... preclude the possi- bility of the pre sence of His at the b inding site. It may be mentioned that the ionization state of amino-acid residues is influenced by their unique microenvironment; therefore, predicting ... medium M19 9 devoid o f fetal bovine s erum and then suspended in 1 mL of the same medium. Then, 100 lgÆmL )1 of either C(YIGSR) 3 -NH 2 or an unrelated pept...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khoa học: "INTEGRATING TEACHING THE ENGLISH TENSE: NAIVE AND FORMAL GRAMMARS IN AN INTELLIGENT TUTOR FOR FOREIGN LANGUAGE TEACHING" pdf
... relation between the time in which the sentence is uttered and the time of the events described in the sentence, but also the relation which holds between the event time and the so called reference ... with the goal of establishing the reliability of the proposed approach. The construction of a new Tutor aimed at teaching the serial theory of tim...
Ngày tải lên: 18/03/2014, 02:20
Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx
... modelling of the Fyn SH3-domain and PAG-derived peptides The interaction pockets of the SH3-domain are made by loops linking the individual b strands together (the RT loop, the n-Src loop, and the 3 10 helix ... positioning of the PxxP core motif of the peptides and 1azg was selected as a template to create models for binding of the PRD1, PRD1-super, and P...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo Y học: Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid pdf
... expression and functional diversity on each PAK isoform in the process of differentiation is in progress. From the fluorescence titration of the mant-GppNHp complex of Rac1 with purified PAK68, the binding ... generating activity of HL-60 Cells Utilizing the induced differentiation of HL-60 promyelo- cytic leukemia cells as a model of myeloid maturation, we examined the...
Ngày tải lên: 31/03/2014, 15:20
Tài liệu Báo cáo khoa học: "Bilingual Terminology Acquisition from Comparable Corpora and Phrasal Translation to Cross-Language Information Retrieval" pptx
... We follow the same steps as the WWW-based technique, replacing the WWW by a test collection and a retrieval system to index docu- ments of the test collection. NTCIR test collection (Kando, 2001) ... instance, the user can access a list of all possible phrases ranked in a form of hier- archy on the basis of word ranks associated to each translation alternative. Selection...
Ngày tải lên: 20/02/2014, 16:20
BÁO CÁO " SINH HỌC CỦA TÔM NƯỚC NGỌT MACROBRACHIUM IDAE (HELLER, 1862) Ở ĐẢO PHÚ QUỐC, VIỆT NAM THE BIOLOGY OF THE FRESHWATER PRAWN " doc
... infrastructure and expansion of tourist sites, and the accumulation of pesticides from agricultural activities in the island may affect the life cycle of the species. It seems to be the first record of ... During the field trips in Phu Quoc Island (Gulf of Thailand) on 26/7/2011 and 9/10/2011, the second author collected many specimens of freshwater prawn...
Ngày tải lên: 02/04/2014, 09:20
Báo cáo y học: "980 nm diode lasers in oral and facial practice: current state of the science and art"
... machines" can replace " ;the brain and hand, skill and experience" of the specialist. The aim of this study was to verify the reliability and efficacy of one of these compact portable diode ... Conclusions: The end results for the use of the 980 nm diode laser in oral and facial sur- gery appears to be justified on the grounds of efficacy a...
Ngày tải lên: 26/10/2012, 09:48