Báo cáo sinh học: " Biomarkers in T cell therapy clinical trials" potx
Báo cáo khoa học: The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines potx
... protracted The extent of treatment-induced growth-arrest was investi- gated in GEO cells only, as inhibition of cell proliferation was not seen in the HCT116 cells. At the end of the treatment ... comparing the total reduction in cell number in cultures treated with CDO and 5-FU together (relative to the SO control) with the expected reduction in Fig. 1. The effect of CDO in HC...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: The influence of cold shock proteins on transcription and translation studied in cell-free model systems pdf
... tightly to the oligodesoxynucleotide hepta-2’-des- oxy-thymidylate (dT 7 ). Therefore, we tested if binding of this nucleotide to TmCSP can interfere with the sug- gested DNA or RNA interaction in the ... transcription process. The effect of cold shock proteins on translation As shown above CSP inhibits transcription in the used concentration range but it could also interfere with protein...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
... p53 mutation. The high sensitivity to DENSPM is interesting in light of the fact that the tumour in the patient was highly refractive to various anticancer treatment r egimens including chemotherapy ... the cells were difficult to discern due to fragmentation. At 72 and 96 h after treatment, it was not possible to detect any intact cells. All cells were also detache d after 48 h of t rea...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo khoa học: Acetylcholinesterase in cell adhesion, neurite growth and network formation pot
... Recent find- ings have revealed that laminin-1 is an interaction partner for acetylcholin- esterase. The binding of acetylcholinesterase to this extracellular matrix component may allow cell- to -cell ... with laminin-1 An adhesive protein is defined by its localization on the cell surface and by the fact that it is involved in binding to other cells or to the extracellular matrix. As out...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways docx
... according to the Ishak modified staging system [28]. Histopathology was inter- preted by two independent board-certified pathologists who were blind to the study. Immunofluorescence staining of HSCs The ... activation by affecting signaling pathways. Enrichment ranking of both signaling pathways and GOs indicated apoptosis to be the most enriched. The miRNA–mRNA interaction network analysis furt...
Ngày tải lên: 30/03/2014, 01:20
Báo cáo khoa học: Gene expression waves Cell cycle independent collective dynamics in cultured cells doc
... 3 reports the first three modes of the RAND data set. It is worth noting the pcrand1 scales with an elutriation cell cycle that is considerably slower (due to the ethanol with respect to the glucose ... component capturing the quasi-totality of the variance. The dual character of this space with respect to the previous analyses implies the projection of the time points on the loading space i...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo y học: "Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome"
... on the prevention of recurrent thrombotic events in patients with APS. The high-intensity warfarin treatment was no more effec- tive than moderate-intensity treatment in preventing recurrent ... time was 3.9±2.0 years. The cumulative incidence of stroke in patients with single antiplatelet treatment was statistically significantly higher than that in patients receiving the combin...
Ngày tải lên: 26/10/2012, 09:48
Báo cáo y học: "Advances in immunomodulating therapy of HBV infection"
... However, although adoptive transfer is an interesting alternative for the treatment of chronic HBV infection, it is associated with certain risks. The risks of adoptive transfer are those associated ... Chien et al. and Saruc et al. suggest that thymosin α-1 may be effective in suppressing viral replication with its effect being delayed until 12 months after the discontinuation of treatm...
Ngày tải lên: 02/11/2012, 11:17
Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"
... intermediate intermediate yes MALDI-TOF <5% intermediate intermediate No intermediate intermediate intermediate yes DNA arrays na intermediate intermediate no high high low yes Indirect methods ... drugs. At the same time, a key challenge is the integration of HBV diagnostic testing with new therapeutic agents in order to ensure optimized, tailored patient treatment. Such integrate...
Ngày tải lên: 03/11/2012, 09:41
Tài liệu Báo cáo khoa học: Changes in purine specificity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2 pptx
... continuing from construct III, we incre- mentally elongated the swapped stretch of amino acids towards the N-terminal, two amino acids at a time, to identify the amino acids that impeded cAMP stimula- CyaB2-GAFB-cAMP rPDE2A-GAF-B-cGMP ... cAMP in the cyaB2 and cGMP in the mPDE2 GAF tandem domain structures are less than 10% exposed to sol- vent, amino acids additional to those identified a...
Ngày tải lên: 19/02/2014, 02:20