Báo cáo hóa học: " Development and preliminary evaluation of the participation in life activities scale for children and adolescents with asthma: an instrument development study" pptx
Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... pre-existing increased insulin resistance and dysfunction of beta cells. Insulin resistance is present in the acutely ill [13,15,18,28] in different intensity, but the factors determining the extent of ... insulin resistance by inducing the release of stress hormones. They also alter insulin receptor signalling [12-16] and create insulin resistance. Due to these actions,...
Ngày tải lên: 25/10/2012, 10:02
Báo cáo khoa học: "Beyond Projectivity: Multilingual Evaluation of Constraints and Measures on Non-Projective Structures" doc
... count how many non-projective edges contain in their gaps a component rooted in an ancestor of the edge (an ancestor of an edge is any node on the path from the root of the whole tree to the parent node ... Mart ´ ı Anton ´ ın. 2002. Design principles for a Spanish treebank. In Proceedings of the 1st Workshop on Treebanks and Linguistic Theories (TLT). Alexa...
Ngày tải lên: 23/03/2014, 18:20
Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx
... was diluted 1 : 20 and incubated for another 2 h at 27 °C, and then for 1 h at 37 °C. Bacteria were washed in NaCl ⁄ P i and cells were infected with Yersinia at an MOI of 60 : 1 for the indicated time ... YpkA and RhoA interact in vitro and whether this protein complex includes OTUB1. YpkA was immunoprecipitated and the presence of OTUB1 and RhoA examined...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx
... Lys169 in H1.4 and H1.5, or Lys170 in H1.3. In mouse, the H1.4 variant has no modifications at Lys26, and at posi- tion 27 there is an alanine, rather than a serine [43]. Ubiquitination and formylation For ... with growth rates [64] and can be significantly increased. The addition of compounds that in uence the cell cycle will cause changes in the levels of ph...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion docx
... cDNA of Chang cells, and the PCR product was sequenced. (D) PCRs for exon 1 and exon 1a were performed in Huh7 and Chang cells. (E) The boundary regions of exon 8 and exon 9 in the genomic DNA of ... are stained cells on the bottom of the Matrigel-coated inserts. The number of invasive cells was determined by counting the number of stained cells and t...
Ngày tải lên: 18/02/2014, 18:20
Báo cáo khoa học: Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor jB1 and mitogen-activated protein kinase pathways doc
... gels and transferred to PVDF membranes. To control the complete and even transfer of proteins to the blotting membranes, membranes were immersed in a Ponceau Red-containing solution and the stained ... Recent advances indi- cate a number of links between the activation of p38 kinase and the DNA checkpoint pathways and their possible interaction in the modulatio...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... H128P, PigE17DCPT1B and HumanD17ECPT1B, and from 0 to 500 lm for D 18PigCPT1B and D28PigCPT1B). The assay was performed at 1 mm carnitine as standard. To analyze PigE17DCPT1B and HumanD17ECPT1B mutants, the assay ... Substitution of glutamate-3 valine-19 leucine-23 and serine-24 with alanine in the N-terminal region of human heart muscle carnitine palmitoyltrans- fer...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate kinase potx
... movement and the ques- tion of whether binding of a single substrate to one of the two domains can also stabilize the structure of the other domain [32–34]. Often the results of studies with the solubilized ... 3-PG and MgADP together in the other case [76] caused merging of the two transitions into a single one. This indicates increased domain cooperativit...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Acute intermittent porphyria – impact of mutations found in the hydroxymethylbilane synthase gene on biochemical and enzymatic protein properties pdf
... amino acids are indicated in red; and the position of the last amino acid before the frameshift is shown in black. The interacting partners of the mutated residues are shown in yellow and the ... dipyrromethane (DPM) cofactor is shown in the ball and stick representation. Magenta indicates the beginning and the end of the region coded by exon 12. The...
Ngày tải lên: 23/03/2014, 04:21
Báo cáo khoa học: Lipid-induced conformational transition of the amyloid core fragment Ab(28–35) and its A30G and A30I mutants docx
... that the binding of the amyloid protein of AD to lipid membranes can change their fluidity [34]. Therefore, we examined the effect of bind- ing of the WT, A30G and A30I peptides on the fluid- ity of ... self-association and to measure distances within proteins and other macromolecules [35]. In order to understand the folding and unfolding of peptides, both in...
Ngày tải lên: 23/03/2014, 07:20