báo cáo hóa học: " Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population" pot

Báo cáo khoa học: Interactions between metals and a-synuclein ) function or artefact? pptx

Báo cáo khoa học: Interactions between metals and a-synuclein ) function or artefact? pptx

... neuronal loss the presence of LBs, containing a- synuclein fibrils, in the substantia nigra and other brain regions are characteristic of the disease [10,11]. Inclusions containing a- synuclein are also found ... study the aggregation properties of a- synuc- lein. Filaments will form from the N-terminal domain of the protein with similar properties the protein...

Ngày tải lên: 07/03/2014, 10:20

9 467 0
Báo cáo khoa học: Intrinsic local disorder and a network of charge–charge interactions are key to actinoporin membrane disruption and cytotoxicity ppt

Báo cáo khoa học: Intrinsic local disorder and a network of charge–charge interactions are key to actinoporin membrane disruption and cytotoxicity ppt

... now hypothesize that actinoporins act in at least two stages: (a) an initial approach to and binding of the mem- brane; (b) oligomerization, pore formation and lysis. We also hypothesize that R29 and Y111 ... substitutions are moderately conservative. The glutamine side chain, despite its lack of positive charge, maintains the polar character and the possibil- ity of...

Ngày tải lên: 14/03/2014, 23:20

10 376 0
Báo cáo khoa học: ""DONNELLAN''''S DISTINCTION AND A COMPUTATIONAL MODEL OF REFERENCE" pptx

Báo cáo khoa học: ""DONNELLAN''''S DISTINCTION AND A COMPUTATIONAL MODEL OF REFERENCE" pptx

... understand the interaction between conventional meaning and a speaker's intentions in such cases, we cannot hope to construct an adequate model of referring and language use in general. ... between the referential and the at- tributive. Barwise and Perry [3], on the other hand, treat their value-loaded/value-free distinction as the central feature of...

Ngày tải lên: 31/03/2014, 17:20

6 376 0
Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

... (marked bold), lands the system into the oscillatory domain, whereas, with a further increase in the stimulus, a single steady state regains stability. The remaining curves in Fig. 5B (red and green) ... conformation, the SH2 domain binds to pY i on the C-terminal tail, and the Src homology 3 (SH3) domain binds to the linker between the SH2 and kinase domains...

Ngày tải lên: 18/02/2014, 11:20

17 513 0
Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx

Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx

... Ala179, Ala180 and Asp183 from one monomer and Arg55¢ from the adjacent monomer corres- pond to E. coli CoaB residues Asn210, Ala275, Ala276, Asp279 and Arg206. A model of human CoaB containing simultaneously ... for D -pantothenate or for its precursor b-alanine. Molecular analysis of the conditional lethality of the dfp-707 mutant revealed a single point mutation w...

Ngày tải lên: 19/02/2014, 12:20

10 491 0
Tài liệu Báo cáo Y học: Electrochemical, FT-IR and UV/VIS spectroscopic properties of the caa3 oxidase from T. thermophilus docx

Tài liệu Báo cáo Y học: Electrochemical, FT-IR and UV/VIS spectroscopic properties of the caa3 oxidase from T. thermophilus docx

... at 415 and 442 nm, and for the oxidized form at 403 and 422 nm. The b–band can be seen at 517 nm and the a band at 547 nm and 603 nm. The difference signals that can be observed between 400 and ... modes from amino acid side chains. For a clearer discrimination of these overlapped bands, we used deuteration of the sample and FT-IR spectra studies in the pr...

Ngày tải lên: 21/02/2014, 15:20

9 529 0
Báo cáo khoa học: Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris ppt

Báo cáo khoa học: Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris ppt

... 4, 170–181. 41. Takada, Y. & Noguchi, T. (1985) Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae ,a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis ... approach allows one to accurately map the metabolic state of the TCA cycle and associated pathways, thus being an important methodological expansion f...

Ngày tải lên: 23/03/2014, 12:20

9 559 0
Báo cáo khoa học: "Comparing Objective and Subjective Measures of Usability in a Human-Robot Dialogue System" potx

Báo cáo khoa học: "Comparing Objective and Subjective Measures of Usability in a Human-Robot Dialogue System" potx

... problems with the sys- tem. The mean age of the subjects was 24.5, with a minimum of 14 and a maximum of 55. Of the sub- jects who indicated an area of study, the two most common areas were Informatics ... questionnaire across all of the subjects, in all cases on a 5-point Likert scale. The subjects in this study gave a generally positive asses...

Ngày tải lên: 17/03/2014, 01:20

9 310 0
Báo cáo khoa học: "Comparing a Linguistic and a Stochastic Tagger" ppt

Báo cáo khoa học: "Comparing a Linguistic and a Stochastic Tagger" ppt

... ous ACL reviewers and UPenn associates, in partic- ular from Mark Liberman. References J-P Chanod and P. Tapanainen. 1995. Tagging French: comparing a statistical and a constraint- based ... experimental evaluations. In the current article, these points of criticism were investigated. A state -of- the- art statistical tagger, capable of performing error-rat...

Ngày tải lên: 17/03/2014, 23:20

8 223 0
Báo cáo y học: "Lifetime health effects and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach"

Báo cáo y học: "Lifetime health effects and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach"

... population and the increase in cardiovascular survival would partially miti- gate the effect of the declining incidence on the total burden of stroke, leading to a further increase in major stroke ... service as compared to usual care, with a central point representing a cost sav- ing of € 5,990 and a QALY gain of 0.51. The point esti- mate for the ICER i...

Ngày tải lên: 25/10/2012, 10:35

10 569 0
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