báo cáo hóa học: "Measuring the impact of health problems among adults with limited mobility in Thailand: further validation of the Perceived Impact of Problem Profile" docx
Báo cáo khoa học: Mitochondrial transcription factor A overexpression and base excision repair deficiency in the inner ear of rats with D-galactose-induced aging pdf
... 5.1-fold, respectively. Increased protein level of TFAM induced by D-Gal To further understand the expression of TFAM protein in the inner ear, western blot analysis was performed. The protein levels of TFAM in the ... in mutant mtDNA harboring the com- mon deletion. By applying the specific probe, we can even detect the presence of the common deletion in the...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx
... elevated in obesity-associated insulin resistance and diabetes, inhibit insulin signalling at several points in the signalling cascade. The liver is critical in maintaining cir- culating glucose ... unfolded a series of events beginning with the TNFa-mediated prevention of the effect of insulin on Foxa2 localization and lead- ing to the abrogation of insulin inhibiti...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: "Measuring Contextual Fitness Using Error Contexts Extracted from the Wikipedia Revision History" pptx
... some point, which are then corrected in subsequent revisions of the same article. The challenge lies in discriminating real-word spelling errors from all sorts of other changes, including non-word ... Filtering The sentence pair filter further reduces the num- ber of remaining sentence pairs by applying a set of heuristics including surface level and semantic level filters...
Ngày tải lên: 17/03/2014, 22:20
Báo cáo khoa học: Human ATP-dependent RNA ⁄ DNA helicase hSuv3p interacts with the cofactor of survivin HBXIP ppt
... absence of HBXIP binding domain resulted in 50% decline in the truncated protein levels within 4 h following inhibition of protein synthesis by cycloheximide. We next wanted to examine whether the presence ... may AB Fig. 5. The role of the C-terminal, HBXIP interacting, domain of hSuv3p in protein stability. (A) The protein stability of the wildtype hSuv3TAP and...
Ngày tải lên: 23/03/2014, 15:21
Báo cáo khoa học: Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA potx
... inhibit growth of the strain even in the presence of IPTG induction. All of these results suggest that the low gene expression associated with NGG codons in the down- stream region following the initiation ... paus- ing at early NGG codons is the reason for the observed low gene expression. The length of the peptidyl moiety of the peptidyl- tRNA in uences...
Ngày tải lên: 30/03/2014, 20:20
Tài liệu Báo cáo khoa học: Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv pdf
... WhiB proteins except WhiB2, the amino acid imme- diately after the C-terminal cysteine of the CXXC motif is proline (Fig. S6). In WhiB2 the absence of proline and therefore of the kink might ... for resistance to intracellular killing, the scavenging of free radicals and the reactivation of degenerated proteins during infection by a family of proteins named ‘thio-...
Ngày tải lên: 18/02/2014, 12:20
Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx
... zinc ions from MT within 20 min [14]. At a con- centration of 1 mm acrolein, all seven zinc ions are released within 6 h. The zinc-releasing activity of other aldehydes was determined with the ... phos- phorylation signaling and gene expression. Results Aldehydes release zinc from zinc-binding proteins The effect of aldehydes on the zinc-binding capacity of zinc proteins was...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 pptx
... at the interface between the a and b subunits. A comparison of the amino-acid sequences showed that the ADP-binding motif in the a subunit of PDH1 clearly differs from that in the a subunit of ... to the a1 subunit of PDH1, though it did contain one ADP- binding motif. This suggests the ADP-binding motif in the a1 subunit mediates the observed ATP binding, an...
Ngày tải lên: 20/02/2014, 01:20
Báo cáo khoa học: Measuring enzyme activities under standardized in vivo-like conditions for systems biology pdf
... at a pH of 6.8 in the absence of phosphatase inhibitors. For the enzymes measured in the reverse direction, the V max values were recalculated in the direction of the flux. To obtain these V max values ... enzyme of interest should be investigated in the context of the in vivo-like medium. Finally, in vivo, the enzymes are present at much higher concen-...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: 15 N-Labelled proteins by cell-free protein synthesis Strategies for high-throughput NMR studies of proteins and protein–ligand complexes doc
... presence of other pro- teins provided in excess at the start of or during the reaction, e.g., for the purpose of rescuing nascently produced insoluble proteins into soluble complexes with soluble binding ... in the case of the C-terminal domain of the s subunit of DNA polymerase III from E. coli, a 16 kDa a-helical protein [10]. Combinatorial [ 15 N]-labelling de...
Ngày tải lên: 07/03/2014, 12:20