... animal models and human beings are needed to un-derstand molecular elements, ligand and receptors, involved in the mode of action of ozone and HBO. Finally, according to the results of this study ... Saline Cefepime Cefepime + HBO Cefepime 4 p.m. Sacrificing Induction of sepsis Rats in the Control, HBO and OT groups re-ceived intraperitoneal inoculums of 1 ml saline con-taining ... CA, USA for cytokines; and USCN Life Science Inc., Wuhan, China for MPO). Histologic evaluation Lung tissues were fixed in formalin for 24 h, embedded in paraffin and cut into 4 µm sections....