báo cáo hóa học: " The assessment of health-related quality of life in relation to the body mass index value in the urban population of Belgrade" potx

Báo cáo khoa học: Plasmodium falciparum merozoite surface protein 1 Glycosylation and localization to low-density, detergent-resistant membranes in the parasitized erythrocyte pdf

Báo cáo khoa học: Plasmodium falciparum merozoite surface protein 1 Glycosylation and localization to low-density, detergent-resistant membranes in the parasitized erythrocyte pdf

... is resistant to the Jack Bean hexosaminidase could be either GPI-linked, N-linked to asparagines or linked to the surface of the protein in a-O-GlcNAc configuration. Two a-O-GlcNAc sites are indeed ... considerable remodelling of the cytoskeleton–membrane interface taking place in the para- sitized erythrocyte [44] makes it difficult to define precisely the relationsh...

Ngày tải lên: 08/03/2014, 08:20

10 415 0
Báo cáo khoa học: Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation pot

Báo cáo khoa học: Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation pot

... extreme modulations of enzyme activities. In particular, in the combinations involving the decrease of glyoxalase II activity the effect is equival- ent to the modulation of the other parameters ... will lead to an increase of the steady-state concentration of methylglyoxal. Again, in the work with yeast referred to above, the most sensitive strain to m...

Ngày tải lên: 23/03/2014, 13:20

11 515 0
Báo cáo khoa học: Esculentin-1b(1–18) – a membrane-active antimicrobial peptide that synergizes with antibiotics and modifies the expression level of a limited number of proteins in Escherichia coli doc

Báo cáo khoa học: Esculentin-1b(1–18) – a membrane-active antimicrobial peptide that synergizes with antibiotics and modifies the expression level of a limited number of proteins in Escherichia coli doc

... min in the dark. After addition of peptide, the increase in fluorescence, owing to the binding of the dye to intracellular DNA, was measured at 37 °C in a microplate counter (Wallac 1420 Victor 3Ô ; Perkin ... Experimental procedures]. To obtain insights into the mode of action underlying the synergistic activity, we investigated the bactericidal action of th...

Ngày tải lên: 16/03/2014, 00:20

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Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx

Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx

... 90% of the total diabetic population, stems from the decreased responsiveness of the body to insulin (insulin resis- tance), accompanied by the failure of pancreatic b-cells to secrete insulin to ... 1A,B). The inhibition of insulin signalling in the liver is pri- marily reflected by the attenuation of the insulin-medi- ated inhibition of gluconeogenic ge...

Ngày tải lên: 16/03/2014, 02:20

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Báo cáo khoa học: Transcriptional activity and Sp 1⁄3 transcription factor binding to the P1 promoter sequences of the human AbH-J-J locus docx

Báo cáo khoa học: Transcriptional activity and Sp 1⁄3 transcription factor binding to the P1 promoter sequences of the human AbH-J-J locus docx

... are able to bind in vitro to P1 promoter sequences of the AbH-J-J gene locus. ChIP assay In order to verify whether the binding of Sp1 and Sp3 proteins to the AbH-J-J P1 promoter occurs in intact cells, ... transcription factors. There is strong evidence demonstrating that transcription fac- tors belonging to the Sp1 family interact with other transcription factors...

Ngày tải lên: 23/03/2014, 07:20

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Báo cáo khoa học: Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells pptx

Báo cáo khoa học: Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells pptx

... Kerala, India. 32 Rajagopal V & Kreitman RJ (2000) Recombinant toxins that bind to the urokinase receptor are cytotoxic with- out requiring binding to the alpha (2)-macroglobulin receptor. J ... us to investigate whether saporin would follow the same route of entry into the cytosol as the related plant toxin ricin [10–12] or the bacterial toxin PEA [2,29]. This would i...

Ngày tải lên: 23/03/2014, 15:21

13 389 0
Báo cáo khoa học: "Automatic Assessment of Coverage Quality in Intelligence Reports" doc

Báo cáo khoa học: "Automatic Assessment of Coverage Quality in Intelligence Reports" doc

... task of assessing the quality of intelligence reports. In this paper we focused on coverage - perhaps the most important aspect in determin- ing which single report to read among several. There ... areas of interest, resulting in several collections of reports. Addi- tionally, the officer may be engaged in many de- cision processes within a small window of time. Give...

Ngày tải lên: 23/03/2014, 16:20

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Báo cáo khoa học: "AN ASSESSMENT EXTRACTED OF SEMANTIC INFORMATION FROM MACHINE READABLE AUTOMATICALLY DICTIONARIES" pptx

Báo cáo khoa học: "AN ASSESSMENT EXTRACTED OF SEMANTIC INFORMATION FROM MACHINE READABLE AUTOMATICALLY DICTIONARIES" pptx

... become increasingly clear that the limited size of existing computational lexicons and the poverty of the semantic information they contain represents one of the primary bottlenecks in the development ... defined concepts: it is virtually meaningless to say that grill is a kind of part, or that corkscrew is a kind of piece. In these cases, the head of the...

Ngày tải lên: 24/03/2014, 05:21

6 333 0
Tài liệu Báo cáo khoa học: A novel nuclear DNA helicase with high specific activity from Pisum sativum catalytically translocates in the 3¢fi5¢ direction docx

Tài liệu Báo cáo khoa học: A novel nuclear DNA helicase with high specific activity from Pisum sativum catalytically translocates in the 3¢fi5¢ direction docx

... the amount of enzyme that unwinds 30% of the DNA helicase substrate at 37 °Cin30min(1 %in one min). For examining the effect of DNA-interacting compounds on DNA unwinding activity of PDH120, the compounds ... This inhibition might be due to the intercalation of the inhibitors into duplex DNA, which results in the formation of DNA–inhibitor complexes that impede...

Ngày tải lên: 20/02/2014, 11:20

11 574 0
Báo cáo khoa học: A thermoacidophilic endoglucanase (CelB) fromAlicyclobacillus acidocaldariusdisplays high sequence similarity to arabinofuranosidases belonging to family 51 of glycoside hydrolases ppt

Báo cáo khoa học: A thermoacidophilic endoglucanase (CelB) fromAlicyclobacillus acidocaldariusdisplays high sequence similarity to arabinofuranosidases belonging to family 51 of glycoside hydrolases ppt

... drawn in relation to the celB region with the restriction sites used for excision of the insert prior to ligation in the host vector (in parentheses). The DNA fragment of pKE25 used for Southern ... promoter detailed in B. The thick vertical bar indicates the end of the ORF in celB trunc . Restriction sites relevant to the cloning strategy are given. A...

Ngày tải lên: 17/03/2014, 10:20

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