... variations in identity (for example ranging from 38–86% in Coprinopsis cine- rea [27]). This natural diversity within in a single organism can be used for protein engineering purpose. In Trametes ... bias in the selec- tion of recombination points. It has been suggested that optimal recombination points allow swapping of structural blocks [19], and combination of large pro- te...
Ngày tải lên: 18/02/2014, 06:20
... The number of joints involved was as follows: 2 joints were involved in 70% of the patients and 3 joints were involved in 30% of the patients. Bilateral in- volvement was seen in 79% of the patients. ... Classification of Chronic Pain; Descriptions of Chronic Pain Syndromes and Definition of Pain Terms, 2 nd ed; Task Force on Taxonomy of the International Associ...
Ngày tải lên: 26/10/2012, 09:07
Báo cáo y học: "Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/ cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma"
... morn- ing [21-24], being consistent with the findings of this study. However, in the NDP group, the pattern of circadian rhythm in 5-FU pharmacokinetics was cer- tainly different from that in ... effects of replacing cisplatin (CDDP) with cis-diammineglycolatoplatinum (nedaplatin, NDP), a second-generation platinum complex, on the pharmacokinetics of 5-fluorouracil (5-FU...
Ngày tải lên: 26/10/2012, 09:53
Tài liệu Báo cáo Y học: Interaction of decorin with CNBr peptides from collagens I and II Evidence for multiple binding sites and essential lysyl residues in collagen pot
... for interaction with decorin is in contrast with the findings that the binding site for decorin is located in a seq uence within the peptide a1(I) CB6 devoid of any Lys/Hyl residue and containing, ... fragment having heparin-binding ability showed interaction with tendon decorin (Fig. 4). Fibronectin is known to interact with decorin protein core [45]. Our data suggest that decor...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo khoa học: Degradation of chitosans with chitinase B from Serratia marcescens Production of chito-oligosaccharides and insight into enzyme processivity docx
... be even-numbered regardless of the initial binding mode, leading to the observed initial domin- ance of even-numbered oligomers. Interestingly, the initial formation of even-numbered oligomers ... preference for A in subsite )2. Catalysis in family 18 chitinases requires distortion of the sugar in the )1 subsite [16]. In analogy with, e.g. lysozyme, a certain minimum amount...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Role of Ca2+/calmodulin regulated signaling pathways in chemoattractant induced neutrophil effector functions Comparison with the role of phosphotidylinositol-3 kinase ppt
... calmodulin and PtdIns3K. In guinea pig neutrophils, it has been demonstrated that inhibition of calmodulin results in inhibition of Rac and p21 activated kinases [50]. Involvement of Rac in ROS ... production of ROS and results in efficient killing of invading pathogens [5]. The effect of the calmodulin inhibitor W7 on fMLP induced ROS production was investigated and compar...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: Interaction of DAPI with individual strands of trinucleotide repeats Effects on replication in vitro of the AATÆATT triplet docx
... characteristic of the TÆT minor- groove than the AÆA minor-groove, in the binding of DAPI [16]. In conclusion, the main cause of the strong inhibitory effect of DAPI on DNA replication in vitro reported in ... sequences within introns can regulate transcription [19,20], the prevalent location of ATT triplet repeats within introns in the human genome [18] suggests strongly...
Ngày tải lên: 16/03/2014, 23:20
Báo cáo khoa học: Association of RNA with the uracil-DNA-degrading factor has major conformational effects and is potentially involved in protein folding pot
... an intrinsic relationship between the RNA binding and protein folding in RNA–UDE. Interestingly, treatment of RNA–UDE with RNa- se A did not result in significant changes of the melting curve, indicating ... to protein folding. To determine whether RNA binding of UDE occurs under physiological con- ditions in the fruit fly, we investigated the presence of UDE in nucleic acid-b...
Ngày tải lên: 22/03/2014, 16:21
Báo cáo khoa học: Interaction of 42Sp50 with the vegetal RNA localization machinery in Xenopus laevis oocytes ppt
... immunopre- cipitate, indicating that the interactions of these differ- ent proteins are likely to be indirect, depending on the presence of intact RNA as integral component of the RNP. Association of 42Sp50 with ... presence of 42Sp50 in nucleus and cytoplasm indicates that it might be a shuttling protein with a function in the nuclear export of localizing mRNAs. To determ...
Ngày tải lên: 23/03/2014, 03:20
Báo cáo khoa học: Incorporation of ZP1 into perivitelline membrane after in vivo treatment with exogenous ZP1 in Japanese quail (Coturnix japonica) doc
... by incubating the membrane with 5% non-fat skim milk in saline buffered at pH 7.4 with 10 mm Tris–HCl containing 0.1% Tween 20 (blocking buffer), and the membrane was incubated with 0.006 lg of ... In comparison with that of Japanese quail, the ZP1 bands in the vitelline mem- brane of chicken (lane 3) and guinea fowl (lane 5) were stained weakly. The weaker staining intens...
Ngày tải lên: 23/03/2014, 07:20