Báo cáo sinh học: " Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients" potx

... 95% CI P FGF2 Low 75 69 NR 68 0.048 1.000 High 30 28 54 50 2. 203 1.108-4.379 0. 024 Missing 3 3 FGFR-1 Low 78 72 NR 61 0.830 High 28 26 NR 62 Missing 2 2 FGF2 & PDGF-B 0.007* Low 27 25 NR 81 ... Rusnati M: Fibroblast growth factor /fibroblast growth factor receptor system in angiogenesis. Cytokine Growth Factor Rev 20 05, 16 (2) :159-178. 9. Ruka W, Rutkowski...

Ngày tải lên: 18/06/2014, 19:20

... 95% CI P FGF2 Low 75 69 NR 68 0.048 1.000 High 30 28 54 50 2. 203 1.108-4.379 0. 024 Missing 3 3 FGFR-1 Low 78 72 NR 61 0.830 High 28 26 NR 62 Missing 2 2 FGF2 & PDGF-B 0.007* Low 27 25 NR 81 ... Translational Medicine 20 11, 9:104 http://www.translational-medicine.com/content/9/1/104 Page 8 of 8 RESEARCH Open Access Fibroblast growth factor 2 orchestrates angiogeni...

Ngày tải lên: 20/06/2014, 04:20

... trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 20 07, 20 : 522 5- 523 2. 12. Colucci G, Giuliani ... 5-FU 29 29 FOLFIRI 21 21 FOLFOX 20 20 Only Cetuximab 12 12 Campanella et al. Journal of Translational Medicine 20 10, 8:36 http://www.translational-medicine.com/conte...

Ngày tải lên: 18/06/2014, 16:20

... EGFR (including EGF, transforming growth factor- a, amphi- regulin and epigen); (b) those that bind to EGFR and ERBB4 (including betacellulin, heparin-binding EGF and epiregulin); and (c) neuregulin ... ligand-binding domain; a transmembrane domain; an intracellular tyrosine kinase domain; and a C-terminal regulatory domain [2] . The extracellular domain is subdivided further into four dom...

Ngày tải lên: 16/02/2014, 09:20

... FG et al. (20 04) Activating muta- tions in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350, 21 29 21 39. 12 Paez JG, Ja ¨ nne ... receptor, thereby inhibiting ligand-dependent EGFR signal transduction; and small- molecule tyrosine kinase inhibitors, such as gefitinib and erlotinib, which target the intracellul...

Ngày tải lên: 16/02/2014, 09:20

... cancers To gain further insights into the role of miR- 125 a-5p in lung carcinogenesis and to examine the clinical rele- vance of our findings, we investigated the expression of miR- 125 a-5p in a panel ... cell growth (Fig. 3A). A B C PC9 01 pEGFR pAkt EGFR Akt β-actin pERK1 /2 ERK1 /2 EGF (20 ng·mL –1 ) + gefitinib (µmol·L –1 ) 010 A549 H 129 9 010 ** ** ** ** ** miR -25 miR -29 b...

Ngày tải lên: 07/03/2014, 00:20

... regulation by protein C inhibitor. FEBS J 27 7, 22 23 22 29. Hepatocyte growth factor activator K. Miyazawa 22 14 FEBS Journal 27 7 (20 10) 22 08 22 14 ª 20 10 The Author Journal compilation ª 20 10 FEBS ... examples of latent growth factors have already been reported. Insulin-like growth factors are inactive when bound to insulin-like growth factor- binding proteins. Trans...

Ngày tải lên: 15/03/2014, 11:20

... Systems, 20 02. http://www.pymol.org Molecular interactions of HGFA with inhibitor ⁄ substrate C. Eigenbrot et al. 22 22 FEBS Journal 27 7 (20 10) 22 15 22 22 ª 20 10 The Authors Journal compilation ª 20 10 ... correspondence of the side chains occupying subsites S1, S2, and S4. Molecular interactions of HGFA with inhibitor ⁄ substrate C. Eigenbrot et al. 22 20 FEBS Journal 27 7 (20...

Ngày tải lên: 15/03/2014, 11:20

... Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor- b, activin, and bone morphogenetic protein-inducible enhancer. J. Biol. Chem. 27 3, 21 145 21 1 52. 42. Dennler, ... assay 922 M. Lutz et al.(Eur. J. Biochem. 27 1) Ó FEBS 20 04 In contrast to TGF-b signaling through receptor serine/ threonine kinases, nerve growth factor (NGF) signals...

Ngày tải lên: 16/03/2014, 16:20

... by protein C inhibitor K. Suzuki 22 28 FEBS Journal 27 7 (20 10) 22 23 22 29 ª 20 10 The Author Journal compilation ª 20 10 FEBS A39339) were compared with the PDB structures of trypsin and serpin, respectively, ... after hepatectomy, suggesting that severe sinusoidal HGFA: its regulation by protein C inhibitor K. Suzuki 22 26 FEBS Journal 27 7 (20 10) 22 23 22 29 ª 20 10 The Author...

Ngày tải lên: 22/03/2014, 21:21