Báo cáo sinh học: " Phosphoproteomic analysis of apoptotic hematopoietic stem cells from hemoglobin E/b-thalassemia" pot

... 2010, 9(11):5848-5858. doi:10.1186/1479-5876-9-96 Cite this article as: Ponnikorn et al.: Phosphoproteomic analysis of apoptotic hematopoietic stem cells from hemoglobin E/b-thalassemia. Journal of Translational Medicine 2011 9:96. Submit ... Journal of Translational Medicine 2011, 9:96 http://www.translational-medicine.com/content/9/1/96 Page 2 of 10 RESEA R C H Open...

Ngày tải lên: 18/06/2014, 19:20

... 2010, 9(11):5848-5858. doi:10.1186/1479-5876-9-96 Cite this article as: Ponnikorn et al.: Phosphoproteomic analysis of apoptotic hematopoietic stem cells from hemoglobin E/b-thalassemia. Journal of Translational Medicine 2011 9:96. Submit ... 9:96 http://www.translational-medicine.com/content/9/1/96 Page 4 of 10 RESEA R C H Open Access Phosphoproteomic analysis of...

Ngày tải lên: 20/06/2014, 04:20

... NOD.Igμ null mice Because of the already described role of T cells causing T1D, pancreata from NOD.Igμ null mice were used for spectratyping analysis and detection of T cell receptor V beta chain ... reconstituted mice. Lack of disease in controls clearly indicated a key role for B cells in the onset of pathology. Phenotypic analysis of lymphocyte infiltrate in the pancr...

Ngày tải lên: 18/06/2014, 19:20

... by immunoblot. Mutational analysis of the putative catalytic and zinc-binding residues of G1L utilizing a trans complementation assayFigure 4 Mutational analysis of the putative catalytic and zinc-binding residues of ... of a zinc ion if such an interaction does in fact occur. Through the use of a library of transiently expressed G1L mutants containing C-termi- nal flag epit...

Ngày tải lên: 19/06/2014, 08:20

... untranslated region of the exon, the mutation has no consequence for the hCDC4 protein. Sequence analysis of hCDC4 exon 10 identifies a new intronic SNP During the analysis of exon 10 and adjacent ... detected mutation in exon 1. Similarly, analysis of samples containing the C/T SNP downstream of exon 10 led to the identification of cleavage products of approximately...

Ngày tải lên: 31/10/2012, 16:49

... expres- sion of Orysata, a JRL from rice. Based on a detailed analysis of its sequence, this lectin was predicted to locate to the nucleocytoplasmic compartment of plant cells, as shown by expression of ... relaxation of the loop regions were carried out by several cycles of steepest des- cent using discover3. After correction of the geometry of the loops using the minimi...

Ngày tải lên: 14/03/2014, 23:20

... the translocation of D -Phe-S-Ppant from GrsA Phe -ATE to TycB1 Pro -CAT. The product of the condensation assay, DKP, is readily extractable into organic solvent [5]. Thus, for a more detailed analysis of the ... to ®ght with loss of enzyme activity and speci®city. A milestone in the study of peptide s ynthetases was the determination of the A-domain structure of GrsA Phe -A...

Ngày tải lên: 17/03/2014, 11:20

... are the result of partial exclusion of the fluorescence from the contractile elements of the muscle. Similar expression is seen in all detectable larval stages (Fig. 8D,F). Feeding of double-stranded ... of mce-1, lines of transgenic nema- todes were created. The basic strategy involved the insertion of several fragments of the 5¢-region of mce-1 into the mul- tiple cloning...

Ngày tải lên: 23/03/2014, 13:20

... Figure 2 Polyermase activity of vRNP complexes of 2009 pandemic H1N1, seasonal H3N2 and WSN H1N1. (a) 293T cells, 37°C. (b) 293T cells, 33°C. (c) A549 cells, 37°C. (d) A549 cells, 33°C. Polymerase ... activity of influenza were mainly conducted on 293T cells [33]. The results of this study showed that in addition to 293T cells, A549 cells can also serve this purpose. Furt...

Ngày tải lên: 18/06/2014, 18:20

... increasing use of the MSIS-29 in research in many parts of the world further analysis of the scale's psy- chometric properties needs to be undertaken. The aim of this study was to use Rasch analysis ... Principal Component Analysis of the residuals to detect the two most disparate subsets of scale items, suggested by posi- tive and negative loadings on the first compone...

Ngày tải lên: 18/06/2014, 18:20