... affectthe function and maturation of DCs. The data show thatexposure of immature DCs to the supernatants results indown-regulation of HLA-DR and costimulatory molecules(CD80), and maturation marker ... Nakatani S, Takeda T, Fukuda K, Tamori A, Habu D, Tanaka T: Prevention of hepatocellular carcinoma inpatients with chronic active hepatitis C and cirrhosis. Lancet2001, 357:196-197.13. Steinman ... course and a poor prognosis [1,2]. Although several treatments suchas tumor resection, liver transplantation, transcatheterarterial chemoembolization (TAE), and local radiofre-quency ablation...