... 50 of whom were lung cancer patients. A range of minimally important differences
(MIDs) in EQ-5D index-based utility (UK and US) scores and VAS scores were estimated using
both anchor-based and ... Central
Page 1 of 8
(page number not for citation purposes)
Health and Quality of Life Outcomes
Open Access
Research
Estimation of minimally important dif...
... of the assay to
demonstrate inhibition of ligand internalization at low
concentrations of CCR2 inhibitor, was determined by
serially diluting the CCR2 antagonist into whole blood
and incubating ... is inhibition of either
receptor signaling or ligand binding, depending on the
mode of action of the drug being examined. When bound
Published: 1 December 2008
Journal of Translatio...
... translation of the
child and parent versions of the KINDL and the ILC.
The following hypotheses were tested in respect of child
and parent reports of QoL in a representative sample of
Norwegian students ... results of an analysis of
unconditional random effects showed that only 3.6% of
the total variance of the ILC LQ0-28 scores and 6.5% of
the total KINDL To...
... more
coordinated manner, increasing movement efficiency and
decreasing movement time of reaches-to-pop. This finding
is consistent with the results of Kaminski [40] who, using
an example of reaching ... contrast, trunk and leg
movements are an essential part of activities such as
dressing, doing laundry, and c ooking whe n performed in
a standing position. For these tasks, gai...
... points).
The FMA gains of patients 2 and 3 were +5 points (from
24 to 29 points) and +8 points (from 11 to 19 points).
These findings were in line with other investigations
about the effects of robot-assisted ... differ in methods and criteria (e.g. interven-
tion time, number of training sessions per week, duration
of training sessions, type of stroke, affected brain side...
... contributions
IM was involved in planning and conducting experiments
as well as data analysis and interpretation and drafting of
the manuscript. NR and IS conducted the tests and were
involved in experimental ... experimental planning. LO was involved in
experimental design, data analysis and interpretation as
well as drafting and revising of the manuscript. IM and L...
... the
present findings of postural instability increasing in both
the L/R and A/P directions. Of primary importance, they
found that the isotropic increment of the COP area
occurred irrespective of whether ... vis-
ual information. In the present study, postural instability
significantly increased during visual rotation, and further
increased during vection perception. Because...
... protein and
peptide were synergistic in killing neurons in the presence
of glial iNOS, in a peroxynitrite and microglia-dependent
mechanism. The addition of the cellular isoform of prion
protein ... endotoxin
(lipopolysaccharide, LPS) and a pro-inflammatory
cytokine (interferon-γ, IFN-γ) or different combinations
of pro-inflammatory cytokines including tumour necrosis
fact...
... CA).
Identification of inhibitor properties
The characteristics of CHEC-9 inhibition were determined
using both classical characterization of inhibitor types,
i.e., the direction of changes in Km and Vmax, and ... the
addition of the substrate solution to the sPLA2 containing
samples. Kinetic parameters including the properties of
CHEC-9 were determined by measuring the init...