báo cáo hóa học: " Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008" pot
Tài liệu Báo cáo khoa học: Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase pdf
... N-terminus instead of a free amino group [32]. Therefore, the asparagine in position 26 was labeled within the intact protein at its a-amino group and represents the amino terminal amino acid of P40. The ... contaminants of the trypsin being used like chymotrypsin or due to pseudotrypsin formed from trypsin by autolysis [28]. These possibilities can be excluded, when th...
Ngày tải lên: 19/02/2014, 18:20
Báo cáo khoa học: Death-associated protein kinase (DAPK) and signal transduction: regulation in cancer ppt
... apoptosis by activating DAPK activity [40]. Indeed, bosutinib, an investigational Src kinase inhibitor, has been shown to inhibit the migration and invasion of breast cancer cells [48]. In addition, ... promoter was found in the CLL cells of affected family members, further reducing the expression of DAPK. The ‘CLL haplotype’ resulted in an increased binding of...
Ngày tải lên: 29/03/2014, 08:20
Tài liệu Báo cáo khoa học: Extended half-life upon binding of destabilized intrabodies allows specific detection of antigen in mammalian cells pdf
... adjusting screening procedures to take into account the conditions found in the cell cytoplasm and to allow the selection of binders of sufficient affin- ity for interacting with their target in the ... As the bound scFv molecules showed an extended half- life, this suggests that the stability of the enzyme was transferred to the binding partners and this ma...
Ngày tải lên: 19/02/2014, 18:20
Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... levels of an isoform of apolipoprotein A-II as a potential marker for prostate cancer. Clin .Cancer. Res.2005; 11:1073-1085. 25. Zeidan BA, Townsend PA. SELDI-TOF proteomic profiling of breast ... (AIHW), Australa- sian Association of Cancer Registries (AACR). Cancer in Aus- tralia. In: Cancer in Australia 2001; Cancer series number 28. Canberra: Australian Insti...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"
... receptor protein containing extra- cellular domains with leucine-rich repeat and a cy- toplasmic signaling domain. The role of TLR4 in in- nate immune response has been well elucidated. The binding ... CCI). The paw withdrawal threshold (PWT) was determined by sequentially increasing and decreasing the stimulus intensity (the ‘up-and-down’ method) (in gram, g), and data wer...
Ngày tải lên: 25/10/2012, 11:48
Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"
... stronger associated with a disability pension case occurring in the latter part of the follow-up period, than would be the case for a disability pension case occurring in the beginning of the ... under-recording in the higher occupational grades may introduce another source of bias. In relation to our study the basic retrospective measure of frequency wa...
Ngày tải lên: 26/10/2012, 10:03
Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc
... was either Arg as in the wild type or Ala as in the L-R90A mutant. It was identical to 1 ⁄ 9A when residue L-90 was Gln as in the germline antibody (Table 4). The canonical structure 1 ⁄ 9A of ... genomic data that are available on anti- bodies and their genes, and performed a systematic scanning of the CDR3 loops of mAb4E11 by mutagen- esis of their residues...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Deciphering enzymes Genetic selection as a probe of structure and mechanism docx
... Monofunctional versions of the dehydratase and the dehydrogenase are provided by plasmid pKIMP-UAUC. Random gene libraries are introduced into this strain and the ability of a cell harboring an individual ... the Claisen rearrangement of chorismate to prephenate, which is the first committed step in the biosynthesis of phenylalanine and tyrosine [11]. In this system...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: "Collecting Highly Parallel Data for Paraphrase Evaluation" doc
... native and fluent contributions, we asked annotators to write the descriptions in the lan- guage of their choice. The result was a significant amount of translation data, unique in its multilingual parallelism. ... annotation task while only 16% of the workers preferred the paraphrasing task. The data produced by the direct paraphrasing task also diverged less, sinc...
Ngày tải lên: 20/02/2014, 04:20
Tài liệu Báo cáo khoa học: "Learning with Unlabeled Data for Text Categorization Using Bootstrapping and Feature Projection Techniques" doc
... for their category, we can finally obtain labeled training data (machine-labeled data) . When the machine-labeled data is used to learn a text classifier, there is another difficult in that they ... contexts from a document, we use sliding window techniques (Maarek et al., 1991). The window is a slide from the first word of the document to the last in the...
Ngày tải lên: 20/02/2014, 16:20