báo cáo hóa học: " Factor structure of the Hospital Anxiety and Depression Scale in Japanese psychiatric outpatient and student populations" pdf

... above. Thus, in the current model the anxiety factor consists of all the original anxiety items and item 7, but the depression factor consists of all the original depression items and item 6. ... and the Hospital Anxiety and Depression Scale. Br J Psychiatry 1990, 157:860-864. 16. Dawkins N, Cloherty ME, Gracey F, Evans JJ: The factor structur...

Ngày tải lên: 18/06/2014, 18:20

... Vpr, and seem to interact with the N-terminal domain of Vpr [6]. In vitro, the (80–96) domain of Vpr forms a complex with the second zinc finger of the nucleocapsid protein NCp7 [7,8]. In vivo, the ... nucleic acids and NCp7. Thus, during the early stages of HIV-1 replication, binding of NCp7 to the C-terminal domain (80–96)Vpr [8] may expose the N-terminal (1...

Ngày tải lên: 31/03/2014, 23:20

... during the differentiation of renal tubules representing the origin of clear cell renal cell carcinoma (RCC) and in the regula- tion of the cell cycle of parietal epithelial cells of the Bow- man's ... of the UCHL1 promoter DNA in the RCC cell line MZ2862RC, characterized by methylation of some of the CpG dinucleotides within the core region of...

Ngày tải lên: 18/06/2014, 15:20

... We were therefore interested in testing this hypothesis and examining whether there is a relationship between psychological distress and vitality. The relationship between the GHQ-12 and the VS ... in old people and has a good factor structure. In addition, this is the first study to test the reli- ability and factor structure of the Subjective Vitality S...

Ngày tải lên: 18/06/2014, 19:20

... resulting in receptor dimerization, activation of the intrinsic receptor tyrosine kinase, and initiation of intracellular signal transduction [14]. Although the EGFR is the primary site of ligand contact, ... only if there were no such constraints used in the structure calculation. The detailed quality of agreement between the structure and the input constrai...

Ngày tải lên: 22/02/2014, 07:20

... metal-binding site at the interface of the two domains, which consists of four side chains: two (His31 and His79) from the N-terminal domain and two (Asp165 and His169) from the C-terminal domain ... counted the interactions, we excluded all residues involved in the binding of the metal cofactor. ApeSODs in different forms were superimposed with the least squar...

Ngày tải lên: 14/02/2014, 22:20

... to the back of the proteinase domain in the crevice between the C-terminal helix, the 204-loop and the 126-loop [7]. The C-terminus of hepsin is elongated by 11 residues in comparison with the ... on the remaining subgroups of the HAT ⁄ HAT-like ⁄ DESC and corin subfamilies exists. We therefore cloned, expressed and purified the serine proteinase domain o...

Ngày tải lên: 19/02/2014, 00:20

... residue in the zinc- bound MshB structure (PDB code 1Q74) adopts a sim- ilar strained conformation. On the other hand, in the absence of a zinc ion in the active site, such as in the structures of the ... and the acetate, and suggests a possible role in the enzymatic reaction which will be discussed later. The structure of the active site, the typ...

Ngày tải lên: 19/02/2014, 00:20

... contacts the methyl groups of methylated CpG. The DNA interface further- more contains several arginine and lysine side chains forming hydrogen bonds with the bases and contacting the DNA backbone. The ... helix on the other face. It is thought that the two inner strands of the b-sheet lie within the major groove of the DNA and that a hydrophobic pocket formed...

Ngày tải lên: 21/02/2014, 00:20

... fragments group together in the vicinity of the N-terminus. This helical patch is the most basic part of the molecule and a potential interaction surface for the preceding acidic N-terminal domain. Structural ... residues of RICH affected by binding of the adenine group (Fig. 5E). Located in the loop between strand b2 and helix a2, Phe239 and Asp241 appear to b...

Ngày tải lên: 07/03/2014, 10:20