Báo cáo sinh học: " The herpes simplex virus UL20 protein functions in glycoprotein K (gK) intracellular transport and virus-induced cell fusion are independent of UL20 functions in cytoplasmic virion envelopment" docx

... Access Research The herpes simplex virus UL20 protein functions in glycoprotein K (gK) intracellular transport and virus- induced cell fusion are independent of UL20 functions in cytoplasmic virion envelopment Jeffrey ... JM, Olivier TL, Kousoulas KG: Herpes simplex virus type-1 (HSV-1) glycoprotein K (gK) and the UL20 pro...

Ngày tải lên: 18/06/2014, 18:20

... which only the processed forms, 4b and 25 K, are localized to the mature virion, both p1 7K and 17 K are observed in the core of mature virus, indicating distinct regulation/func- tion of VV proteolysis ... product, a virion membrane protein while the 13 kDa peptide matched with the A14L protein. The sequence of the 21 kDa peptide represents a cleavage...

Ngày tải lên: 18/06/2014, 18:20

... and pseudotyping. J Virol 2001, 75:7175-7183. 27. Sandrin V, Muriaux D, Darlix JL, Cosset FL: Intracellular traffick- ing of Gag and Env proteins and their interactions modulate pseudotyping of retroviruses. ... co-localization of A- MLV Env and MoMLV core proteins in the endocytic path- way in late endosomes including multivesicular bodies (MVBs). They suggest that the...

Ngày tải lên: 19/06/2014, 08:20

... diversity in the marine RNA virus community remains uncharacterized. Furthermore, these results raise the hypothesis that the genomes of these marine RNA viruses that we propose to infect single-celled ... of the organisms in the sea; therefore it is unlikely that viruses infecting these organisms make up a significant fraction of the natural RNA virioplankton. Marine...

Ngày tải lên: 18/06/2014, 18:20

... been observed in the C-terminal of the ATP binding domain [54] and in the N-terminal of the peptide binding site [55], which may be involved in the interaction with the lipid bilayer. Therefore, ... forms of the 38-kDa molecule. Sakoonwa- tanyoo and colleagues [41] identified a laminin-binding protein of 50-kDa on the surface of C6/36 cells as a candi- da...

Ngày tải lên: 18/06/2014, 18:20

... immuno- logical response toward input capsids in the absence of new viral protein synthesis. If so, altering the rate of intra- cellular trafficking and uncoating of rAAVs by the use of specific drugs or ... (AAV2) in 1982 [7] and the pioneering work on the successful cloning of AAV establishing the foundation of recombinant AAV vectors capable of expressin...

Ngày tải lên: 18/06/2014, 18:20

... (arrow). Electron micrograph of HCV and HIV-1 extracellular parti-cles in the vicinity of a K7 cellFigure 5 Electron micrograph of HCV and HIV-1 extracellular particles in the vicinity of a K7 cell. Representative ... outside the cells. The assembly and synthesis of HHV-6A begins in the nucleus, the virion acquires a mem- brane as it passes through the...

Ngày tải lên: 18/06/2014, 18:20

... 1 of the pseudoknot is bipartite and carries an intervening loop between stem 1a and stem 1b. The length of the stem 1 a and b in BVDV are 6 and 7 bp, respectively. To inves- tigate whether the ... reminiscent of those of the classical swine fever virus, a pestivirus, and the hepatitis C viruses, another genus of the Flaviviridae. Conclusion: The IRES...

Ngày tải lên: 18/06/2014, 18:20

... neuroinvasive in adult mice following intra- peritoneal (i.p.) inoculation[6]. In contrast of the investi- gations of the North-American WNV strains, the virulence phenotype of Israeli strains of ... genetic subtypes: the lineage II (enzootic strains from tropical Africa and Madagascar island) and the lineage I (tropical african strains) that caused the outbreaks...

Ngày tải lên: 18/06/2014, 22:20