... paper and was critical to study design and completion. All authors have read and approved the final manuscript.Author disclosure statementNanhai G. Chen, Qian Zhang, Yong A. Yu, and Aladar A. ... non-invasive imaging of virotherapy alters the replication and oncolytic capability of a novel vaccinia virus, GLV-1h153.Methods: GLV-1h153 was modified from parental vaccinia virus GLV-1h68 to carry ... including breast tumors [6],mesothelioma [7], canine breast tumors [8], pancreaticcancers [9], anaplastic thyroid cancers [10 ,11 ], mela-noma [12 ], and squamous cell carcinoma [13 ].Materials and methodsVirus...