Báo cáo sinh học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" potx
Báo cáo sinh học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" potx
... HPIV1 wt and rHPIV1 mutant viruses containing the indicated mutations in the P/C, HN and L genes in a multiple cycle growth curve. Monolayer cultures of LLC-MK2 cells and Vero cells were infected ... cells, making manufacture of these vaccines commercially feasible. In the present study, two new rHPIV1 viruses containing single att mutations in L, L 17 1...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" docx
... cells, making manufacture of these vaccines commercially feasible. In the present study, two new rHPIV1 viruses containing single att mutations in L, L 17 10 11 and L Y942A , were generated and ... to the level of temperature sensitivity in vitro and attenuation in vivo. The rHPIV1 mutant bearing the indi- vidual att mutation L 17 10 11 (rHPIV1-C R84G...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo sinh học: " Transcription and translation of human F11R gene are required for an initial step of atherogenesis induced by inflammatory cytokines" doc
... increases in the level of F11R mRNA in inflamed endothelial cells resulted from the de novo expression of F11R by conducting experiments involving the pretreatment of endothelial cells with the ... Ϭ Ϭ͘ϭ Ϭ͘Ϯ Ϭ͘ϯ Ϭ͘ϰ Ϭ͘ϱ Ϭ͘ϲ Ϭ͘ϳ Ϭ͘ϴ ŶŽŶͲ ƚĂƌŐĞƚŝŶŐ ƐŝZE &ϭϭZ ƐŝZE ŶŽŶͲ ƚĂƌŐĞƚŝŶŐ ƐŝZE &ϭϭZ ƐŝZE F11R protein normalized to tubulin levels (lysate) HAEC HUVEC Figure 6...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo khoa học: Mechanisms and kinetics of human arylamine N-acetyltransferase 1 inhibition by disulfiram potx
... Identification of the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) as a new target of cisplatin in breast cancer cells: molecular and cellular mechanisms of inhibition. Mol Pharmacol 73, ... used clinically in the treatment of chronic alcoholism since 19 48 [1] (Fig. 1) . DS acts by irreversibly inhibiting the hepatic aldehyde dehydro- genase, l...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Folding and turnover of human iron regulatory protein 1 depend on its subcellular localization pdf
... dense particles in the following. The use of polyclonal antibodies recognizing hIRP1 (Fig. 2B,C) resulted in heavy and uniform labelling of all inclusion bodies, which clearly indicated the associ- ation ... stained. Lane 1, recombinant human IRP1; lanes 2– 11 , fractions 1 10 of the sucrose gradient. (B) Western blot of the same fractions. Lane 1, recombinant h...
Ngày tải lên: 07/03/2014, 10:20
Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
... including glucosamine and chondroitin, one month prior to study and during the study, other than multivitamin and mineral supplements containing vitamins and minerals as the sole medicinal ingredients ... typically worsens with weight bearing, including walking and standing, and improves with rest (4). Other symptoms include morning stiffness and gelling of the invo...
Ngày tải lên: 26/10/2012, 09:48
báo cáo sinh học:" Burnout and use of HIV services among health care workers in Lusaka District, Zambia: a cross-sectional study" pot
... (0.8 1. 2) 1. 0 (0.7 1. 3) Age 16 –25 years 14 (82.4%) 3 (17 .7%) 1. 4 (1. 0 1. 7) 1. 5 (1. 0 1. 7) Age >45 years 91 (52.9%) 81 (47 .1% ) Ref Ref ART clinic 30 (63.8%) 17 (36.2%) 1. 2 (0.9 1. 5) 1. 4 (1. 0 1. 6) Inpatient ... utilization of HIV-related health services, staff emphasized the need for multiple options, since one approach was unlikely to meet the needs of all...
Ngày tải lên: 18/06/2014, 17:20
Báo cáo sinh học: " Detection and frequency of recombination in tomato-infecting begomoviruses of South and Southeast Asia" pptx
... [Y8] Tomato yellow leaf curl China virus- Tb [Y25] AJ457985 TYLCCNV-Tb [Y25] Tomato yellow leaf curl Thailand virus- [1] X63 015 TYLCTHV- [1] Tomato yellow leaf curl Thailand virus- [2] AF1 419 22 TYLCTHV-[2] Tomato ... leaf curl China virus- Tb [Y10] AJ 319 675 TYLCCNV-Tb [Y10] Tomato yellow leaf curl China virus- Tb [Y 11] AJ 319 676 TYLCCNV-Tb [Y 11] Tomato yellow leaf curl China...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo sinh học: " Construction and characterization of recombinant flaviviruses bearing insertions between E and NS1 genes" docx
... < 16 < 16 YF17D/Esa/5.1glic 20 10 0 80 ± 47 37 – 211 80 15 8 ± 1, 144 26 – 3,535 19 9 Earle's Medium 15 0 < 10 < 10 0 < 16 < 16 * Reciprocal of the dilution yielding 50% plaque ... also allow in vivo studies on flavivirus cell and tissue tropism as well as cellular processes related to flavivirus infection Materials and methods Cell cultures Vero...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo sinh học: "Construction and characterization of an infectious clone of coxsackievirus A16" docx
... stain. The availability of a CVA16 infectious clone will greatly facilitate the investigation of the genetic determinants of its virulence. This clone will also allow the rapid, rational development ... Wild -type virus R1 virus R2 virus Wild -type virus R1 virus R2 virus Wild -type virus Figure 7 M, DL15000 DNA marker (TaKaRa Biotechnology, Dalian, Ch...
Ngày tải lên: 18/06/2014, 18:20