... nucleosomes to modifythe a ccessibility of factors to limited DNA regions presentin a nucleosome [3]. Histone modifying enzymes dictatecombinations of post-translational modifications ofhistones to ... recogni-zing and binding to specifically modified histones is i nsupport of this hypothesis [7,55].The histone code is probably in a ction in spermatogeniccells as stage-specific histone modifications ... C., Faure, A.K., Usson, Y., Pelletier,R.,Sele,B.,Khochbin,S.&Rousseaux,S.(2000)Regulatedhyperacetylation of core histones d uring mouse sp ermatogenesis:involvement of histone deacetylases....