Báo cáo hóa học: "Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference" pdf

... ADAM 10 expression in SACC-LM cells To investigate whether ADAM 10 expression was essen- tial for the metastatic capability of SACC-LM cells, stable ADAM 10 RNAi transfected cells (SACC- ADAM1 0-RNAi) ... supporting theroleofADAM10incellgrowthinSACC-LMcells (Figure 5 C). In addition, the affect of gene silencing of ADAM 10 on the cell migration ability...

Ngày tải lên: 18/06/2014, 16:20

... overall survival of treated animals (Figure 6D). These results confirm the anti-tumor activity of anti-VLC therapy, as observed by others, and further support the use of anti-CD52 therapy in humans. Discussion Our ... of complement; (1) In the presence of Alemtuzumab and heat inacti- vated sera, the majority of VLC are viable Annexin V (-) and PI (-) cells. In c...

Ngày tải lên: 18/06/2014, 15:20

... compare the internal consistency of item responses, factorial validity and invariance and the convergent and known-groups validity of the child-report version and the parent-report version of the ... analyses and wrote the man- uscript. BK and URS were the principal investigators of the study; they designed the study's concept and supervised the...

Ngày tải lên: 18/06/2014, 19:20

... cases. In 82.8% of cases, the proxy was the mother and in 11.4% it was the father. The mean age of mothers was 41.9 years and the mean age of fathers was 44.9 years. The real household income ... compare the internal consistency of item responses, factorial validity and invariance and the convergent and known-groups validity of the child-report version a...

Ngày tải lên: 18/06/2014, 19:20

... effects of RES on the growth of serum- stimulated HepG2 cells. As shown in Table 1 and 2 and Figure 1A and Figure 1B, the MTT assay indicates that RES inhibits significantly the growth of serum-stimulated HepG2 ... of CAV1. A solution of 228 mg (1.0 mmol) of RES in 10 mL of acetone was added into a mixture of 1 g of K 2 CO 3 and 10 ml acetone in N 2 a...

Ngày tải lên: 18/06/2014, 15:20

... in the design of the study and revised and drafted the manuscript. MC participated in study design and coordination and revised and drafted the manuscript. AM participated in the design of the ... study and revised and drafted the manuscript. IDD participated in the design of the study and revised and drafted the manuscript. WMK participated in stud...

Ngày tải lên: 18/06/2014, 15:20

... transport, and the number of Th17 cells was determined by flow cytometry. Depicted are the plots of gated Th17 cells from patient NRA12. The left column is the baseline pre-dosing sample, and the right ... treatment received and the outcome after therapy. Two thirds of the patients had M1c metastatic melanoma (visceral metastasis and/ or high LDH), and m...

Ngày tải lên: 18/06/2014, 15:20

... concentra- tions of AlPcS 2 (1 -10 μM) in HBSS at 37°C. After incuba- tion of cells in HBSS, both the absorption and fluorescence spectra (exc. 610 nm; em. 625-800 nm) of cells and supernatant before and ... and analyzed using the software provided by Opti- mas Corporation, USA. Cytoplasmic and nuclear localization of the sensitizer was estimated by analyz...

Ngày tải lên: 18/06/2014, 16:20

... safety and effectiveness as well as a thorough under- standing of the underlying mechanism of actions. The use of an animal model of acute IS, therefore, is imperative to investigate the short and ... of CXCR4 and SDF-1α in BIA, ADMSC therapy also mark- edly increased the cellular expression of vWF that is a marker of endothelial cells. Importantly, ADMSC therap...

Ngày tải lên: 18/06/2014, 16:20

... database, designed and performed the statistical analysis and wrote the man- uscript. HW and WW contributed to the development of the study design and advised about the performance of the statistical ... Stroke Impact Scale and others. The psychometric properties of these scales are often investigated using classic test theory where a raw score is generally use...

Ngày tải lên: 18/06/2014, 18:20