Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc
Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc
... immunity. The priming strategy could then be matched with heterologous vectors that expand and/ or differentiate the primed cells to therapeutically useful effector T cells or, alternatively, with homologous ... et al.: Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8 + T cell immunity. Journal of...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học:" Stem cells from umbilical cord blood do have myogenic potential, with and without differentiation induction in vitro" pdf
... fundamental for their future utilization for therapeutic purposes. The experiments showed here, demonstrated that the hematopoietic stem cells from umbilical cord blood have the potential to fuse to ... was maintained in growth media [36]. The present results of co-culture of CD34+ and DMD myoblasts without the inductive media show that these cells can interact and express d...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology" pot
... (but not hyper-acute) rejection suggests that TSD encompasses at least two separate components: the activation of ISGs and the broader attraction and in situ activation of innate and adaptive immune ... therapy are extrapolated into a two phase equation estimating the concomitant rate of tumor regression and growth. This kinetic regres- sion/growth model estimates accura...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab" doc
... guidelines to evaluate the response to treatment in solid tumours. European Organization for Reserch and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute ... this treatment in terms of activity and efficacy. We studied a population of patients mainly treated with chemotherapy plus Cetuximab, 42% of whom treated as first line tr...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Vaccination with a plasmid DNA encoding HER-2/ neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial" pptx
... months following vaccination. This variation in treatment was due to the fact that conco mitant trastuzumab admi nis- tration was allowed, but not an integrated part of the experimental treatment. ... pre- Her2-vaccination (15.8) and post-Her2-vaccination (13.9) samples, indicating that the TT booster vaccina- tion resulted in stable cellular immunity to TT over the treatment peri...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis" pot
... induction of Th1 and Tc1 responses. The current study also tested the effects of additional vaccinations at the same location. Th1 cells culminated after the 3 rd vaccination and outnumbered Th2 ... statistical tests and played an important role in the data analysis. MEJ carried out patient recruitment, randomization and logistics of the data collection. CLS was t...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " MMP-1 is a (pre-)invasive factor in Barrettassociated esophageal adenocarcinomas and is associated with positive lymph node status" doc
... currently unknown. The cell that gives rise to Barrett metaplasia is not known. Recently, it has been hypothesized that intestinal metaplasia may arise from a change in the differentia- tion pattern ... carcinogenesis of Barrett’s esophagus. However, to date there are no experimental data that support this hypothesis [11]. Additionally, the findings of elevated gene and protein...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Abstract Despite new additions to the standard of care therapy for high grade primary malignant brain tumors, the prognosis for patients with this disease is still poor." ppt
... recruiting patients, there are currently 12 institu- tions participating in the conduct of the Phase II study that is completing treatment and follow-up of 141 enrolled patients http://clinicaltrials.gov/ct2/show/ record/NCT00045968[55]. ... and another at Penn State University (NCT00990496), evaluate the safety and patient response to intravenous adoptive transfer with auto...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Utility values for symptomatic non-severe hypoglycaemia elicited from persons with and without diabetes in Canada and the United Kingdom" potx
... complied with the tenets of the Declaration of Helsinki. Standardised Descriptions of Health States The derivation of health states was split into developmen- tal and validation phases. In the developmental ... perfect health, the greater the burden attributed to the health state [18]. Respondents As there is no consensus whether persons naïve to the dis- ease under...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Patient experiences with oily skin: The qualitative development of content for two new patient reported outcome questionnaires" doc
... the development of a new PRO, it is important to assess its psychometric properties in the population of interest, to provide evidence of its ability to detect change over time and to attempt ... skin, consistent with the treatment satisfaction focus groups, a large proportion of the participants (68%, n = 37) reported that their oily skin felt "unclean", "dir...
Ngày tải lên: 18/06/2014, 19:20