Báo cáo hóa học: "DNA polymeraseh protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy" pot

... et al.: DNA polymeraseh protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy. Journal of Translational ... RESEARC H Open Access DNA polymeraseh protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma...

Ngày tải lên: 18/06/2014, 16:20

... Camphausen K: Urinary VEGF and MMP Levels As Predictive Markers of 1-Year Progression- Free Survival in Cancer Patients Treated With Radiation Therapy: A Longitudinal Study of Protein Kinetics Through- out ... group of 10 healthy donors was included. Serum PSA was used as a surrogate treatment response marker. Exosomes present in urine were quantified, and expression...

Ngày tải lên: 18/06/2014, 15:20

... mRNA levels of the anti-inflammatory genes IL-4 and TGFb1. Absence of C/EBPb results in significant decreases in LPS-induced expression of NOS2 and in LPS+IFNg-induced expression of NOS2 and IL-1b. ... treat- ment, and in nuclear levels of both activating (Full/LAP) and inhibitory ( LIP) C/EBPb isoforms 24 h after treat- ment. The increases in C/EBPb mRNA and protei...

Ngày tải lên: 19/06/2014, 22:20

... the manuscript and statistical analysis. RU assisted in microRNA array and expression studies and analysis. HM helped with the ELISA and technical editing of the manuscript. TAR, JM and MTL participated ... from Healthy Donors and Patients with GBM This study was approved by the local ethical review board of University of Pittsburgh. All healthy donors and Sasaki e...

Ngày tải lên: 18/06/2014, 16:20

... quantification of AQP4 expression. Markers of active inflammation (macrophages, BBB permeability, and interleukin-1b) and markers of scarring (gliosis) were also quantified. Results: This animal model of ... associated with an inflam- matory reaction around t he site of the injection with a breakdown of the BBB [13]. Rats were anesthetized with an intrap eritoneal inje...

Ngày tải lên: 19/06/2014, 22:20

... distribution, random sampling without replacement, and joint distribution of ranks. The notion of NOD random variables was introduced by Lehmann [3] and developed in Joag-Dev and Proschan [2]. ... sequence of random variables. According to the sentence above, a sequence of strictly stationary and NA random variables is acceptable. Another interesting example of a sequence {Z...

Ngày tải lên: 18/06/2014, 15:20

... animals with CNE2 treated with cisplatin. 2, animals with CNE2 treated with normal saline. 3, animals with CNE2/shABCC2-1 treated with cisplatin. 4, animals with CNE2/shABCC2-1 treated with normal ... mRNA and protein expressions of ABCC2 in NPC cellsFigure 1 Special siRNA targeting ABCC2 silences the mRNA and protein expressions of ABCC2 in NPC cells. (A)...

Ngày tải lên: 18/06/2014, 15:20

... The similarities with the recordings made in patients are out- standing. Furthermore, this model might serve in the future for the deciphering of motor commands and neural representations of movement, ... excitability, such as I h and I t , they could simulate the range of frequencies of tremor recorded from patients. The increase in these currents resulted in alternating bu...

Ngày tải lên: 18/06/2014, 15:20

... mean survival of patients exhibiting tumor tissue TRIP-Br2 overexpres- sion (9 months) was found to be significantly lower than the survival of HCC patients without evidence of TRIP-Br2 overexpression ... which TRIP-Br proteins promote growth and tumor progression. As overexpression of TRIP-Br2 resulted in the transforma- tion of NIH3T3 fibroblasts, we hypothesized that TR...

Ngày tải lên: 18/06/2014, 15:20

... and cytology of mice treated with the sigma-2 ligand, SV119, and conventional chemotherapy. Peripheral blood was drawn from tumor-bearing mice 24 hours after treatment with a single dose of ... for pancreas cancer and are an exciting class of compounds for potential treatment of these malignancies. Methods Sigma receptor ligands Sigma-2 specific ligands SV119, SV95,...

Ngày tải lên: 18/06/2014, 15:20