Báo cáo hóa học: "Evaluation of six CTLA-4 polymorphisms in highrisk melanoma patients receiving adjuvant interferon therapy in the He13A/98 multicenter trial" docx

... analyzed the potential influences of the CTLA-4 genotype upon the outcome of IFN adjuvant therapy, on the basis of prior suggestions of the role of certain polymorphisms of the CTLA-4 gene and other immunotherapies ... further explored in other trials of IFN-a2b of the US and European cooperative groups. Our investigation into the association of CL...

Ngày tải lên: 18/06/2014, 16:20

... determining for each signal intensity on the chip its quantile in the chip’ s intensity distribu- tion and replacing that value with the value having that quantile in the reference distribution. In ... computing the mean of the remaining log intensity values. It is less susceptible to the effects of extreme values. In our experiments, we used a trimming percentage o...

Ngày tải lên: 18/06/2014, 16:20

... RGDechiHCit in the selective inhibition of endothelial a V b 3 integrin in vitro and in vivo. Such inhibition opens new fields of investigation on the mechanisms of angiogenesis, offering clinical ... importance of RGDe- chiHCit i n the selective inhibition of endothelial a V b 3 integrin. Such inhibition opens new fields of investiga- tion on the mechanisms of ang...

Ngày tải lên: 18/06/2014, 16:20

... difficulty staying asleep reported that they were frequently awakened during the night due to the pain of FM. Participants also spoke of no longer feeling refreshed upon awakening since having FM, regardless ... had initially diagnosed them with FM. Responses to the screening questions indicated that 18 of the participants experienced pain every day, and the remaining 2 partic...

Ngày tải lên: 18/06/2014, 18:20

... patients were defined. In the absence of published thresholds, the following groups of patients were defined based on the distribution of the changes in both the weekly sleep inter- ference and pain diaries ... [32]. The weekly mean sleep inter- ference score and the weekly mean pain score at baseline were used to define groups of patients differing in severi...

Ngày tải lên: 18/06/2014, 19:20

... Quality of life measured with the Profile of Quality of Life in the Chronically Ill (PLC) revealed mean values for capacity of performance in the patient group in the same range as in the control ... 50–60%). The main proportion of the unmar- ried patients were not in a steady relationship, in the male patients this ratio was as high as 95%. While nea...

Ngày tải lên: 18/06/2014, 22:20

... current position of the robot end-point in the virtual environment. The robot end-point is the point at the top of the robot where the grasping mechanism is attached to the robot. When the subject ... provide information about the direction of the in tended movement. These forces were assessed from the time the ball reached the center of the table to...

Ngày tải lên: 19/06/2014, 08:20

... processing the synthesized signal, using three different processing schemes. The naked eye inspec- tion reveals that the processing scheme including comb- filtering and artifact blocking window ... extracted from the hybrid signal, and underlined the importance of the artifact blocking window module in the process. The results of this work have direct implications on th...

Ngày tải lên: 19/06/2014, 10:20

... 3) ρ max of the subjects feeling VIMS decreased at the same point of time on both days. 4) After repetitions of watch- ing the same video image, the ρ max of TS-down group increased at the middle ... from the first day to the third day for more than half of all the subjects (TS-down group). 2) There were some subjects whose intensity of VIMS increased as the num...

Ngày tải lên: 19/06/2014, 10:20

... of the study, assisted in the recruitment of subjects, did the testing, participated in data analysis and drafting of the manuscript. SB participated in the design of the study, assisted in the ... and wrote the manuscript. IW participated in the design of the study, recruited subjects, did the testing, participated in data analysis and drafting of...

Ngày tải lên: 19/06/2014, 08:20