Báo cáo hóa học: " Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation" pot

... 8:90 http://www.translational-medicine.com/content/8/1/90 Page 11 of 13 RESEARC H Open Access Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation Maja Bürdek, Stefani Spranger, Susanne Wilde, ... Th1- Polarizing Dendritic Cells Using the TLR7/8 Agonist CL075. J Immunol 185:738-747. doi:10.1186/1479-5876-8-90 Cite this article...

Ngày tải lên: 18/06/2014, 16:20

... 108(18):2212-2218. 19. Food and Drug Administration: Guidance for Industry: Potency tests for cellular and Gene Therapy Products. Center for Bio- logics Evaluation and Research. US Department of Health and Human Services; ... (TSB) used for the culture of anaerobic and fungi/aerobic bacteria (THIOC-T and TSB-T, bioMerieux SA, Switzerland) was performed by incubating two vi...

Ngày tải lên: 18/06/2014, 15:20

... corresponding results of Yang [9] for NA random variables and Wang et al. [10] for NOD random variables. In Section 3, we will study the complete convergence for acceptable random variables using the ... for acceptable random variables generalizes and improves the corresponding results presented by Yang for NA random variables and Wang et al. for NOD random variables. Using...

Ngày tải lên: 18/06/2014, 15:20

... number not for citation purposes) and ovarian cancer and was used for SNP analysis and val- idation by direct sequencing (Figure 2). To demonstrate the principle, data were portrayed for individual ... location and genomic mapping of the BRCA1 locus and sub-fragments amplified for genomic analysisFigure 1 Chromosomal location and genomic mapping of the BRCA1 locus and su...

Ngày tải lên: 18/06/2014, 15:20

... microtubules and intermediary fila- ments, as well as keratin 5 and 15. We also looked for genes involved in cell adhesion and migration and found integrin alpha 3, integrin beta 2 and intercellular ... we found genes with key functions for mismatch and double-strand DNA repair such as proliferating cell nuclear antigen, mutS homolog 6 replication factor C 4 and C5, RAD51 a...

Ngày tải lên: 18/06/2014, 15:20

... differentially within bone marrow and periph- eral blood cells of selected individuals (Table 2). Spot No. 5 (14-3-3 related) was only present in patient C, spot No. 121 and 122 (TCHTP and variant) was only ... solution for the overlay contained 20% glycerol and 2% CA. Focus- ing started with 200 V for 15 minutes, followed by 300 V for 30 minutes and finally with 400 V for...

Ngày tải lên: 18/06/2014, 15:20

... CD4+CD25+ T cells compared to that in CD8+CD25+ T cells. The CD4+CD25+Foxp3+ T cells expressed CD44 and CD62L, showing their effector and memory phenotypes. Both FoxP3- responder T cells and CD4+FoxP3+ ... healthy donors. Stimulator cells were irradiated (5000 rad) and cultured with responder cells for 8 days in the presence of 10 M BrdU (BD Pharmingen). Cells were th...

Ngày tải lên: 18/06/2014, 15:20

... 28 and 112 J/cm 2 of human peripheral blood mononuclear cells, a heterogeneou s population of T cells, B cells, NK cells, and monocytes has been described to induce chro- matin relaxation and ... He-Ne-based laser for adherent cells that may be useful in regeneration such as fibro- blasts and mesenchymal stem cells. Studies have also been performed in vi tro on immu- nologic...

Ngày tải lên: 18/06/2014, 16:20

... required for cell signaling inhibitors should not be a limitation. Thus, patient selec- tion for driver mutations, emergence of resistance, timing and durability of responses, and the need for chronic therapy ... among various stakeholders and an orga- nized effort to derive the maximum information from clinical trials. This also requires a willingness to share information and m...

Ngày tải lên: 18/06/2014, 16:20

... death and DNA fragmentation in gastric epithelial cells To investigate the relations of PAR-2 expression, cell death, and DNA fragmentation, cells were transfected with AS ODN for PAR-2 and cultured ... of various cells including pancreatic and gastric cancer cells, and smooth muscle cells [23-25]. Additionally, activation of PAR-2 by agonist or activating peptide protect...

Ngày tải lên: 18/06/2014, 16:20