Báo cáo hóa học: " cDNA targets improve whole blood gene exp

Báo cáo hóa học: " cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis" ppt

... 8:87 http://www.translational-medicine.com/content/8/1/87 Page 4 of 12 RESEARC H Open Access cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis Mark L Parrish 1* , ... completed all of the extraction of total RNA from blood samples. BL provided project and...

Ngày tải lên : 18/06/2014, 16:20

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báo cáo hóa học:" Drugs targeting the mitochondrial pore act as citotoxic and cytostatic agents in temozolomide-resistant glioma cells" pptx

... normal braintissuesample1;NB2,normalbraintissuesample2; GBIV, WHO grade IV glioblastoma; E/G, mean ratio of densitometry values of EGFR and GAPDH amplification bands. P/G, mean ratio of densitometry values of PTEN and GAPDH amplification ... Organisation for Research and Trea tment of Cancer Brain Tumor and Radiotherapy, Groups, National Cancer Institute of Canada Clinical...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx

... in a majority of metastatic cases, in tumor cells and associated stromal cells. Pancreatic cancer Enhanced expression of RAGE and HMGB1 in the setting of metastases. Lung and esophageal cancers ... between inflammatory pathways and pathways promoting tumor- igenesis and metastasis. Characterizing the role of RAGE in vivo and in vitro can be broadly applied to a varie...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học: " Can we derive an ''''exchange rate'''' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique" doc

... measures and a generic measure of health st atu s to a preference-based measure of HRQoL in a sample of Australians with a diagnosis of acute stroke. This will allow quantification of the additional ... Station, Texas STATACorp LP; 2005. 26. Hawthorne G and Osborne R: Population norms and mean- ingful differences for the Assessment of Quality of Life (AQoL) measure...

Ngày tải lên : 18/06/2014, 18:20

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báo cáo hóa học: " Child-OIDP index in Brazil: Cross-cultural adaptation and validation" pot

... oral and general health status variables (self- rated oral health, satisfaction with oral health, perceived oral treatment needs, and self-rated general health), through the use of the Kruskal-Wallis ... The aim of this study was to carry out a cross-cultural adaptation of the Child- OIDP index and to assess its reliability and validity for application among Brazilian children...

Ngày tải lên : 18/06/2014, 19:20

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báo cáo hóa học: " How do medical students value health on the EQ-5D? Evaluation of hypothetical health states compared to the general population" ppt

... procedures have to be approved; (4) monitoring and establishing population health status locally, nation- ally and internationally [8]. The standard approach of the EuroQol group to establish health ... Participation was voluntary and anonymous. Ethical approval was obtained from the institutional review board. We used the German version of the EQ-5D for which data of the general...

Ngày tải lên : 18/06/2014, 19:20

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báo cáo hóa học: " The Psychosocial Screen for Cancer (PSSCAN): Further validation and normative data" pptx

... health status. Sample 1 was the large sample (n = 570) of cancer patients described in the original manuscript [10]. Sample 2 was a small in-patient sample of cancer patients, and Samples 3 and ... have con- ducted additional analyses to recommend specific cut-off scores and have also gathered data from healthy, normative adult samples so that both the clinical and healthy nor...

Ngày tải lên : 18/06/2014, 19:20

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báo cáo hóa học: " Human CNS cultures exposed to HIV-1 gp120 reproduce dendritic injuries of HIV-1-associated dementia Sam Iskander1, Kimberley A Walsh1 and Robert R " docx

... sets. Statistical analysis For quantification of MAP2 and GFAP staining in the CSLM images, data were analyzed by Student's t-test. Data obtained from assays of apoptosis, necrosis and cellular proliferation ... of the study. RH, SI and KW designed and carried out the experiments and collected and analyzed the data in the laboratory of RH. RH, SI and KW co-wrote the...

Ngày tải lên : 19/06/2014, 22:20

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báo cáo hóa học: " Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer''''s disease" potx

... IL-1R, and therefore have similar activities. Both are capable of inducing inflammatory cascades in-vivo and in-vitro, and it has been shown that they are capable of up-regulating expression of astrocyte-derived ... amyloid load in transgenic mouse models of Alzheimer's disease Nikunj S Patel*, Daniel Paris, Venkatarajan Mathura, Amita N Quadros, Fiona C Crawford and...

Ngày tải lên : 19/06/2014, 22:20

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báo cáo hóa học: " Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice" pptx

... Thioflavin-S), = 25 µm (CD11b, GFAP)) Focal microglial activation is indicated by black arrows. Focal astroglial activation within the parenchyma by black arrows and at the side of of a brain ... purposes) Comparison of A deposition, micro- and astroglial activationFigure 1 Comparison of A deposition, micro- and astroglial activation. (A) Representative detection of A 1...

Ngày tải lên : 19/06/2014, 22:20

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