Báo cáo hóa học: " Effective knowledge management in transla

Báo cáo hóa học: " Effective knowledge management in translational medicine" doc

... role of cyclin D1 in metastatic melanoma in single cohort using k-means clustering (a,b). Szalma et al. Journal of Translational Medicine 2010, 8:68 http://www .translational- medicine.com/content/8/1/68 Page ... set of translational and biomarker groups and focusing also on the management and mining of the data emanating from integrative settings crossing the drug discovery and dev...

Ngày tải lên : 18/06/2014, 16:20

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báo cáo hóa học:" The least core in fixed-income taxation models: a brief mathematical inspection" doc

... voting over income distributions as in Grandmont [8]. Conditions (2) and (3) insure that every tax is increasing with the revenues in such a way that it does not change the post-tax income ranking. ... (Marhuenda and Ortu˜no-Ortin [6]), considering solution concepts less demanding than the core (De Donder and Hindriks [10]). In a majority game in coalitional form of voting over income...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học:" Hypothetical membrane mechanisms in essential tremor" pdf

... patients is determined by both I h and I T . Tremor frequency increases with increasing I h and decreases with increasing I T . In summary, simulations support our hypothesis that an increase in premotor ... we introduce a concept explaining the basis of oscillations in reciprocally innervated circuits when external inhibition is intact. Concept 2 – Increased excitability can make rec...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học:" Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells" docx

... Hematoxylin and Eosin stain of tumor and surrounding brain (lower right, scale bar = 100 μm). Tumor volume is 30 mm 3 . Journal of Translational Medicine 2008, 6:80 http://www .translational- medicine.com/content/6/1/80 Page ... caliber vein that is minimally where influenced by in- flow and partial volume averaging effects. Since the transit time of blood movement between an artery an...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học:" GJB2 mutation spectrum in 2063 Chinese patients with nonsyndromic hearing impairment" pptx

... (Jilin province), Yin- chuan School for the Blind, Deaf and Dumb (Ningxia Province), Xining Spe- cial Education School (Qinghai province), Changan School for the Deaf and Dumb (Shaanxi province), ... groups in China As indicated in Table 2, the frequency of GJB2 mutations varies from 4% in Guangxi to 30.4% in Jiangsu. These Amino acid alignment of Connexin26 in different speciesFig...

Ngày tải lên : 18/06/2014, 15:20

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báo cáo hóa học:" Survivin gene levels in the peripheral blood of patients with gastric cancer independently predict survival" doc

... associated with Survivin levels indicates the increase in risk of death for 100 fold increase in Survivin expression (Table 3). Since only these four independent variables were retained by the Cox ... treatments. Our findings are of particular relevance also from the tumor biology viewpoint because the Survivin gene encodes a key anti-apoptotic protein belonging to the inhibitor of apopto...

Ngày tải lên : 18/06/2014, 15:20

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Báo cáo hóa học: " Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice" pptx

... immunity and including cytokine support for T cells can induce effective anti-tumor responses against orthotopic and metastatic tumors. Introduction Immunotherapies involving combinations of ... antitumor activity resulting from inclusion of IL-2 in therapy, we determined the relative proportions of activated T cells in tumor-draining lymph nodes. This was achieved by determining the...

Ngày tải lên : 18/06/2014, 16:20

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Báo cáo hóa học: " Non-monotonic changes in clonogenic cell survival induced by disulphonated aluminum phthalocyanine photodynamic treatment in a human glioma cell line" pot

... AlPcS 2 following incubation of cells with AlPcS 2 in HBSS for different time intervals showed rapid and linear increase in the accumulation of AlPcS 2 in the first 2 h, prolonged incubation (up ... to microtubular (MT) network since it has been shown that MT disruption is involved in apoptosis [50,51]. Depo- lymerization of tubulin may be caused by an increase in PDT induced intra...

Ngày tải lên : 18/06/2014, 16:20

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Báo cáo hóa học: " First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP321 (LAG-3Ig) enhances immune responses and antitumor activity" pptx

... randomized clinical studies with an internal paclitaxel alone control group will determine whether the differences observed in the pre- sent study in terms of clinical benefit hold true. The clinical ... granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res 2001, 61:3689-3697. 6. Zhong H, Han B, Tourkova IL, Lokshin A, Ros...

Ngày tải lên : 18/06/2014, 16:20

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Báo cáo hóa học: " Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment" pptx

... TRIF (TIR- domain-containing adapter-inducing interferon-b)join- ing the RIG-I/MDA5 pathway. In the other pathway, TLR7 senses single-strand HCV RNA and via the MyD88 adaptor protein activates ... to inactivate the cellular protein toll-interleukin-1 receptor d omain-containing adaptor inducing IFN ( TRIF). TRIF is an adaptor protein t hat is a critical component of the TLR3 signaling ... f...

Ngày tải lên : 18/06/2014, 16:20

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