Báo cáo hóa học: " Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice" pptx
Báo cáo hóa học: " Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice" pptx
... reproduc- tion in any medium, provided the original work is properly cited. Research Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice Jennifer ... article as: Westwood et al., Three agonist antibodies in combina- tion with high-dose IL-2 eradicate orthotopic kidney cancer in mice Journal...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders" pptx
... a severe inflammatory demyelinating disorder, has gained increasing interest since the discovery of serum NMO-IgG autoantibodies targeting the aquaporin-4 (AQP4) water channel protein [1, 2]. ... demonstrating the induction of an NMO-like disease following immunization of certain rat strains with MOG [21-23]. Whereas in humans anti-MOG antibodies in MS have been extensively inves...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis" docx
... S: CD44 stimulation induces integrin-mediated adhesion of colon cancer cell lines to endothelial cells by up- regulation of integrins and c-Met and activation of integrins. Cancer Res 1999, 59:4427-34. 24. ... expression of a dis- tinct proangiogenic protein profile, including the specific expansion of a LFA-1-expressing cancer cell subpopula- tion able to interact with ICAM-1-express...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients" potx
... (IGF1R): Insulin-like Growth Factor-1 receptor; (IGFBP-3): Insulin-like Growth Factor Binding Protein-3; (IGFBP-4): Insulin-like Growth Factor Binding; Protein-4; (MAPK): Mitogen-activated protein kinase; ... the insulin-like growth factor binding proteins and the IGFBP proteases in modulat- ing IGF action. Endocrinol Metab Clin North Am 1996, 25(3):591-614. 35. Rajaram S, Baylink DJ, Mohan...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure" pot
... cardiac intensive care with the cath- eter remaining in place for drug initiation and monitoring as per standard care. Exclusion criteria included exposure to intravenous inotropic support within ... tro- ponin may reveal sub-clinical cardiac injury due to ino- trope initiation. We sought to determine the effect of initiating milrinone on biomarkers of myocardial func- tion (N-terminal pr...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways" ppt
... dur- ing virus replication. Our bioinformatics analyses indicate that a coordinated expression of PI3K with protein tyrosine kinases, serine- threonine kinases and other signaling proteins in our experimentally ... the RGD domains are present in numerous integral plasma membrane proteins identified in this study including integrin and other cell adhesion proteins [82]. In addition,...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" yuDetecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients" pot
... uncertain which of these, either individually or in combination, is the etiological agent for inducing p-STAT-3 in PBMC. Alternatively, there may be other yet-unidentified factors that induce ... p-STAT-3 staining. The negative control was created by omitting the primary antibody from the immunohistochemical analysis and replacing it with the protein-block serum-free solution. Three...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Increased shedding of HU177 correlates with worse prognosis in primary melanoma" pdf
... angiopoietin-2 (sAng-2) as useful predictors of response to therapy. In a study of 59 patients with meta- static melanoma o r renal c ell carcinoma receiving high dose recombinant interleukin-2 (IL-2) , ... studies in a larger, independent cohort. Acknowledgements Written informed consent was obtained from all patients at the time of enrollment. Study findings were, in part, supported...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells" ppt
... [38]. Regarding virulence factors of H. pylori, cagA and vacuolating cytotoxin A (vacA) are reported to contri- bute to gastric cancer incidence [39,40]. Since H. pylori in Korean isolates, HP99 used in ... e the mechanism of gastri c carcino- genesis involving PAR-2-associated prevention against apoptosis of gastric epithelial cells infected with H. pylori containing different isotyp...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation" pot
... higher in cocultures using D C that had an increased duration of peptide loading, indicating that 24 h of peptide loading provided DC with higher amounts of HLA-A2-peptide ligand, resulting in better ... al: A new dendritic cell vaccine generated with interleukin-3 and interferon-beta induces CD8+ T cell responses against NA17-A2 tumor peptide in melanoma patients. Cancer Immunol...
Ngày tải lên: 18/06/2014, 16:20