Báo cáo hóa học: "An integrative paradigm to impart quality to correlative science" pdf

... this article as: Kalos: An integrative paradigm to impart quality to correlative science. Journal of Translational Medicine 2010 8:26.Submit your next manuscript to BioMed Centraland take full ... 8:26http://www.translational-medicine.com/content/8/1/26Page 9 of 10REVIEW Open AccessAn integrative paradigm to impart quality to correlative scienceMichael KalosAbstract Correlative studies are a primary mechanism through which ... tablish quality in correlative laboratories is to explicitly supporta l aboratory environment that supports qualit y. To thatend, specific guidelines might include: (a) Develop SOPfor all laboratory...

báo cáo hóa học: " An exploratory study to evaluate the utility of an adapted Mother Generated Index (MGI) in assessment of postpartum quality of life in India" potx

... 30.5 to 60.2), MSEC-51.6%(95%CI 22.1 to 80.1), LSEC-83.7% (95%CI 65.4 to 93.3)], likely depression [HSEC-27.7% (95%CI 22.0 to 34.3), MSEC-22.3% (95%CI 5.8 to 57.0), LSEC-54.4%(95%CI 48.0 to 60.7)] ... Score3.2(1.8 to 4.5) Secondary index Score2.6(1.9 to 3.3)EPDS Score (n = 172)10.9 (9.7 to 12.0)EPDS Score 9.5 (8.9 to 10.1) EPDS Score 9.3 (5.9 to 12.8) EPDS Score 13.4 (12.8 to 13.9)*Data ... specifications it wasdecided to restrict the number of areas identified to six, to keep the scoring points at 10, to allow 12 spending pointsand to allow the mother and child counselors to adminis-ter the...

Báo cáo y học: "An Avian Connection as a Catalyst to the 1918-1919 Influenza Pandemic"

... progenitors for future generations of the virus [15]. Knowing this we may be able to predict which strains may be likely to be the progenitors for future strains in future outbreaks. The predictor ... it infects to fight the virus. The first two factors are influenced by the genetics of the virus. The last factor is dependent on the health of the host to regulate a response to the virus. ... pig to pig by taking mucus from the secretions from the upper respiratory tract of infected pigs to healthy pigs. Richard Shope, working with the Rockefeller Institute of Comparative Anatomy...

Báo cáo khoa học: "An Unsupervised Dynamic Bayesian Network Approach to Measuring Speech Style Accommodation" doc

... refer to as theDirectInﬂuence (DI) factor, with values True(T) and False (F), and the second factor is theinclusion of links from style states to and fromAccommodation states, which we refer to ... segmentedinto analysis windows of 50ms, where adjacentwindows overlapped by 40ms. From each anal-ysis window a total of 7 features were com-puted: voice probability, harmonic to noise ratio,voice quality ... Fraw0,Fenv0), and loudness. A 10-bin histogram of fea-ture values was computed for each of these fea-tures, which was then normalized to sum to 1.0.The normalized histogram effectively representsboth...

báo cáo hóa học:" Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells" pot

... protein that begins mitosis localized to the centromeres but at the onset of anaphase relocates to the spindle equator [4]. Aurora-B kinase is known to regulate processes such as kinetochore and microtubuleinteractions ... phosphorylated by Aurora-B kinase upon entry intomitosis [54,55]. We used immunocytochemistry to deter-mine the percentage of cells positive for histone H3 phos-phorylated on Serine 10 (pH3S10) ... aneuploidy, possi-bly due to the inhibition of other family members such asAurora-B. Thus, in addition to inhibiting mitotic entry,VE-465 appears to induce apoptosis by causing cata-strophic...

báo cáo hóa học:" An intron 9 containing splice variant of PAX2" pptx

... cycleat 72°C for 2 min was performed. For quantification, PCRproducts were cloned into the vector pCR2.1-TOPO (Inv-Journal of Translational Medicine 2009, 7:36 http://www.translational-medicine.com/content/7/1/36Page ... in mRNAexpression levels may not automatically lead to significantdifferences in protein expression.Detection of the new splice variant by Western Blot To verify the expression of this intron ... lines.However, in blood samples of healthy volunteers bandscorresponding to the known splice variants of PAX2 and to a lesser extent to the new splice variant could be alsodetected. Expression of PAX2...

Báo cáo hóa học: " A quantitative real time PCR method to analyze T cell receptor Vb subgroup expansion by staphylococcal superantigens" doc

... al enterotoxins (SEs), SE-like (SEl) toxinsand toxic shock syndrome toxin-1 (TSST-1), producedby Staphylococcus aureus, are prototypic microbialsuperantigens (SAgs). Members of this toxin subgroup* ... Bohach1*AbstractBackground: Staphylococcal enterotoxins (SEs), SE-like (SEl) toxins, and toxic shock syndrome toxin-1 (TSST-1),produced by Staphylococcus aureus, belong to the subgroup of microbial superantigens ... 105 to 2.5 copies/reaction; from left to right). The non-templatecontrol (NTC) showed no amplification. The threshold was automatically set by Sequence Detector Systems version 1.2.2 software to...

Báo cáo hóa học: " An exploratory investigation of the influence of publication on translational medicine research" pot

... translational pathway?: We undertook an exploratory exercise to determine where basic and translational medical research is currently published. Original research articles (329 in total) published in ... next challenge is to ensure the pathway operates efficiently and does not allow promising innovations to languish and to provide a smoother transition for interventions to reach the clinic ... appropriate and influential in the progression of anintervention. To investigate if this is possible we under-took an exploratory exercise to determine where basicand translational medical research...

báo cáo hóa học: " Feasibility and acceptance of electronic quality of life assessment in general practice: an implementation study" pdf

... health record, into a specific lab results page,printed, or rendered into a PDF (portable document for-mat) document to be displayed on the doctors' screen or to be added to a paper file ... time to inform patients and to discuss HRQoL data in a busy general practice, and thepaucity of resources to alleviate HRQoL deficits. Thoughthe electronic tool reduces workload compared to a ... daily routine [12]. Asthma patients, too,showed an impaired quality of life in the SGRQ compared to the general population [25], with different patterns insymptoms, activity and the impact of the...

báo cáo hóa học: " Development of a self-reporting tool to obtain a " docx

... the four f actor structure obtained is aninteresting tool to clarify the clinical aspects of thefibromyalgia syndrome. A test-retest reliability andvalidity (confirmatory factorial analysis) ... on exploratory factor ana-lysis. The aim was to simplify and reduce the number ofitems of each scale according to their internal consis-tency and complementation with the global tools used.With ... with the new tool, in relation to other variablesobtained by hetero-ass essment. Calculation was made ofthe score obtained by each patient in relation to each ofthe factors obtained. To this effect,...

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