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Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot

Báo cáo hóa học:

Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot

... phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ... 8 of 9RESEA R C H Open AccessA randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with ... of combination therapy with estra-mustine, mitoxantrone, and vinorelbine in patients with CRPC. One study demonstrated a potential clinical ben-efit to adding estramustine with vinorelbine as...
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báo cáo hóa học: " A randomized trial of a lifestyle intervention in obese endometrial cancer survivors: quality of life outcomes and mediators of behavior change" pptx

... lower disinhibition score, indicating anincrease likelihood to overeat in the presence of disinhib-itors. This was an unexpected finding and may indicatethat there are still certain triggers ... havebeen influenced by all study patients participating in anorientation meeting, in addition to meeting with the prin-cipal investigator at the 3 measurement time points. Itmay be that simple increased ... randomized controlled trial comparing a lifestyle intervention (LI) consisting of exer-cise and nutritional counseling with cognitive-behaviormodification to usual care (UC) in overweight and...
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báo cáo hóa học: " A pilot study evaluating use of a computer-assisted neurorehabilitation platform for upper-extremity stroke assessment" pptx

... perception-action coupling and func-tional motor tasks: perception of environmental con-straints, motor planning and execution, and correctivemonitoring of performance including explicit feedback[10]). ... compo-nent in the activities of daily livings (ADLs) (e.g. eating,drinking, grooming) which involve arm movements.Many studies have examined point-to-point reaching in subjects with stroke-induced ... CV:Trends in length of stay, living setting, functional outcome, and mortality following medical rehabilitation. JAMA 2004,292(14):1687-95.13. Levin MF: Interjoint coordination during pointing movementsis...
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báo cáo hóa học: " Adalimumab improves health-related quality of life in patients with moderate to severe plaque psoriasis compared with the United States general population norms: Results from a randomized, controlled Phase III study" pdf

... randomized, controlled Phase III trial evaluating the effect of adalimumab in patients with psoriasis (N = 1,205). Patients with moderate to severe psoriasis were randomized in a 2:1 ratioto adalimumab ... NH, and MKW designed and interpreted theanalysis of health-related quality of life data. AM and SFassisted Abbott Laboratories with the original Phase IIIstudy design and acquisition of data. ... 52-week, Phase III clinical trial in adult patients with moderate to severe chronic plaque psoriasis[23]. Patients were randomized in a 1:2 ratio to receivesubcutaneous injections of placebo only or...
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Báo cáo y học: "A Randomized Study of Epithelial Ovarian Cancer: Is Chemotherapy Useful after Complete Remission"

... The toxicity in treatment with Cisplatin consisted of nausea and vomiting in 38 patients (62.3% of Cisplatin-treated patients) ; this was WHO grade 3 in 17 pts (27.9%) and grade 4 in 10 pts (16.4%); ... Wiltshaw E, Evans B, Rustin G. A prospective randomized trial comparing high-dose cisplatin with low-dose cisplatin and chlorambucil in advanced ovarian carcinoma. J Clin Oncol 1986;4:722-729. ... Padua with a thesis in collaboration with the Mario Negri Institute in Milan and continues to cooperate with the ICON studies. Martin Donach, having completed his B.A. in Biochemistry at New York...
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báo cáo hóa học:" A highly invasive human glioblastoma pre-clinical model for testing therapeutics" pot

... measuring tumorgrowth potential [25], with systemic injection for measur-ing invasive and metastatic growth potential in EMLassays [51], or with orthotopic administration of tumorcells for measuring ... levels of cytokines and growth factors in GBM-M2 cellsThe expression of a number of factors and interleukins isincreased in patient GBM and is associated with gliomastage and aggressive tumor ... (GibcoTM, InvitrogenCorporation, Carlsbad, CA) supplemented with 10% fetalbovine serum (FBS) (Invitrogen Corporation) and peni-cillin and streptomycin (Invitrogen Corporation).Recovery of invasive...
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báo cáo hóa học:" A systematic approach to biomarker discovery; Preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers"" docx

... NCI/FDA/iSBTcsponsored workshop tied to the annual meeting of the iSBTc to be held in Washington DC in theFall of 2009. This foreword provides an overview of the task force and invites feedback ... quality of the material will remain a primaryfocus of the working group, the need for platform stand-ardization or, at least comparability of results to facilitateinter -trial, inter-institutional ... been organizedunder the leadership of Peter Lee and Francesco Marincolaaimed at the identification of experimental, bioinformat-ics and clinical strategies to increase the yield of informa-tion...
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báo cáo hóa học:" A novel role of HLA class I in the pathology of medulloblastoma" docx

... Binding of β2m or a specific antibodyto open forms of HLA class I promoted phosphorylation of ERK1/2 in medulloblastoma cell line with high levels, but not in the cell line with low levels of ... conformation). Binding of extracellular β2m to open conformer releases the receptor, enabling full blown signaling indicated by increased phosphorylation (P) of intracellular portion of the ... tumors, 3oat cell lung carcinomas, one each of ependymoblastoma and lymphoma, and 20 tissues of brain metastases fromtumors of various origin. IRB approval was obtained forthe construction and...
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báo cáo hóa học:

báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx

... regeneration.Materials and methodsTesting were performed in the quality control laboratory of the cell therapy unit of the Cardiocentro Ticino. TheLaboratory is authorized and regularly inspected by ... thatcould originate from the starting or raw materials or adventitiously introduced during the manufacturing proc-ess. In any case, a thorough testing must be performed atthe level of finished ... manufacturerprior to the completion of tests for conformity with stand-ards applicable to such product, including potency. Thecurrent regulations allow for considerable flexibility in determining the...
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báo cáo hóa học:

báo cáo hóa học:" A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data" potx

... theSNP information of the subjects). Given a training set of instance-label pairs, the SVM algorithm maps the trainingvectors into a higher dimensional space by employing akernel function and ... months of persistentfatigue resulting in substantial reduction in the person'slevel of activity [2-4]. Furthermore, in CFS, four or more of the following symptoms are present for 6 months or more: ... CRHR1 = corticotropin releasing hormone receptor 1, CRHR2 = corticotropin releasing hormone receptor 2, MAOA = monoamine oxidase A, MAOB = monoamine oxidase B, NR3C1 = nuclear receptor subfamily...
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