Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot

... phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ... 8 of 9 RESEA R C H Open Access A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modu...

Ngày tải lên: 18/06/2014, 16:20

... lower disinhibition score, indicating an increase likelihood to overeat in the presence of disinhib- itors. This was an unexpected finding and may indicate that there are still certain triggers ... have been influenced by all study patients participating in an orientation meeting, in addition to meeting with the prin- cipal investigator at the 3 measurement time points. It may b...

Ngày tải lên: 18/06/2014, 19:20

... perception-action coupling and func- tional motor tasks: perception of environmental con- straints, motor planning and execution, and corrective monitoring of performance including explicit feedback [10]). ... compo- nent in the activities of daily livings (ADLs) (e.g. eating, drinking, grooming) which involve arm movements. Many studies have examined point-to-point reaching in...

Ngày tải lên: 19/06/2014, 08:20

... randomized, controlled Phase III trial evaluating the effect of adalimumab in patients with psoriasis (N = 1,205). Patients with moderate to severe psoriasis were randomized in a 2:1 ratio to adalimumab ... NH, and MKW designed and interpreted the analysis of health-related quality of life data. AM and SF assisted Abbott Laboratories with the original Phase...

Ngày tải lên: 18/06/2014, 19:20

... The toxicity in treatment with Cisplatin consisted of nausea and vomiting in 38 patients (62.3% of Cisplatin-treated patients) ; this was WHO grade 3 in 17 pts (27.9%) and grade 4 in 10 pts (16.4%); ... Wiltshaw E, Evans B, Rustin G. A prospective randomized trial comparing high-dose cisplatin with low- dose cisplatin and chlorambucil in advanced ovarian carci...

Ngày tải lên: 03/11/2012, 09:57

... measuring tumor growth potential [25], with systemic injection for measur- ing invasive and metastatic growth potential in EML assays [51], or with orthotopic administration of tumor cells for measuring ... levels of cytokines and growth factors in GBM-M2 cells The expression of a number of factors and interleukins is increased in patient GBM and is associated w...

Ngày tải lên: 18/06/2014, 15:20

... NCI/FDA/iSBTc sponsored workshop tied to the annual meeting of the iSBTc to be held in Washington DC in the Fall of 2009. This foreword provides an overview of the task force and invites feedback ... quality of the material will remain a primary focus of the working group, the need for platform stand- ardization or, at least comparability of results to facilitate inter -tri...

Ngày tải lên: 18/06/2014, 15:20

... Binding of β2m or a specific antibody to open forms of HLA class I promoted phosphorylation of ERK1/2 in medulloblastoma cell line with high levels, but not in the cell line with low levels of ... conformation). Binding of extracellular β 2 m to open conformer releases the receptor, enabling full blown signaling indicated by increased phosphorylation (P) of intracellula...

Ngày tải lên: 18/06/2014, 15:20

... regeneration. Materials and methods Testing were performed in the quality control laboratory of the cell therapy unit of the Cardiocentro Ticino. The Laboratory is authorized and regularly inspected by ... that could originate from the starting or raw materials or adventitiously introduced during the manufacturing proc- ess. In any case, a thorough testing must be performed at...

Ngày tải lên: 18/06/2014, 15:20

... the SNP information of the subjects). Given a training set of instance-label pairs, the SVM algorithm maps the training vectors into a higher dimensional space by employing a kernel function and ... months of persistent fatigue resulting in substantial reduction in the person's level of activity [2-4]. Furthermore, in CFS, four or more of the following symptoms are pr...

Ngày tải lên: 18/06/2014, 15:20