Báo cáo hóa học: "Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy" pdf

... 8:10 http://www.translational-medicine.com/content/8/1/10 Page 6 of 11 RESEARC H Open Access Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy Vladia Monsurrò 1 , ... two MxA-positive and two MxA negative samples (Figure 4B). Adenoviral infection of PDAC cell lines To assess th...

Ngày tải lên: 18/06/2014, 16:20

... scores are first transformed into norm-based scores that have been standardized to the 1998 general United States (US) pop- ulation for a mean of 50 and a standard deviation of 10. A regression ... prevalence of many illnesses. For example, the prev- alence of a wide-range of psychiatric disorders is easily more than double than that found in the community [1]. About 2% of the...

Ngày tải lên: 18/06/2014, 19:20

... prevalence of many illnesses. For example, the prev- alence of a wide-range of psychiatric disorders is easily more than double than that found in the community [1]. About 2% of the U.S. general ... 000 health states. Using the standard gamble, 611 members of the United Kingdom (UK) general population valued a 249 subset of these states, and a model was then devel- oped to defin...

Ngày tải lên: 18/06/2014, 19:20

... Preferences for each health state were elicited from a representative group of members of the general public in the UK. Methods Development of health states Existing health state descriptions of metastatic ... study of a similar study design conducted in a sample of 100 members of the general public in the UK demonstrated a low variance (SD range = 0.22–0.29) across utilit...

Ngày tải lên: 18/06/2014, 19:20

... Passos-Bueno MR, Vainzof M, Marie SK, Zatz M: Half the dys- trophin gene apparently enough for a mild clinical course: confirmation of its potential use for gene therapy. Hum Mol Genet 1994, 3:919-922. 5. ... cells: 1 fold DMD/DMB muscle cells), co-cultures were performed with 50% of the medium used for CD34+ stem cells and 50% of the medium used for myoblasts. They were e...

Ngày tải lên: 18/06/2014, 15:20

... software. For comparison of PAX2 intron 9 specific mRNA expression levels significance was esti- mated by the 2-sided Mann-Whitney U test for compari- son of two different groups. Detection of ... deletion of the last 89 amino acid residues. Alternative processing represents an important mechanism for the generation of various pro- tein isoforms with different functions from...

Ngày tải lên: 18/06/2014, 15:20

... integrity of the tubal epithelium are of paramount importance for the develop- ment of a unique microenvironment required for optimal fertilization and early embryo development. They are therefore ... may represent a new potential source of pluripotent cells for regenerative medicine. The identification of niches of tis- sue-specific stem cells capable of replacing damag...

Ngày tải lên: 18/06/2014, 15:20

... mechanisms of action and effects of both Andro and LA for treatment of diabetes, we con- ducted experiments to evaluate the efficacy and possible mechanism(s) of action of a conjugate of Andro ... immunohistochemical analysis of pancreatic islets were performed. Translocation of glucose transporter subtype 4 in soleus muscle was detected by western blot. In RIN-m cells in...

Ngày tải lên: 18/06/2014, 15:20

... included review of the accuracy of the data in the case report forms. Journal of Translational Medicine 2009, 7:68 http://www.translational-medicine.com/content/7/1/68 Page 5 of 11 (page number not for citation ... concentration-time profiles of EMD 273063Figure 1 Mean serum concentration-time profiles of EMD 273063. Mean serum concentration-time profiles after daily 4-h infu- s...

Ngày tải lên: 18/06/2014, 15:20

... reasoning for the hypothesis that explains the CRP cycles in terms of homeostatic immune regulatory cycles. This knowledge might also open the way for improved timing of treatment(s) for improved ... days, irrespective of the amplitude of the CRP levels. The ampli- tude has been the main focus of previous cancer studies, principally because of the fact that close serial meas...

Ngày tải lên: 18/06/2014, 15:20