Báo cáo hóa học: " A pilot clinical trial testing mutant von HippelLindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma" doc
Báo cáo hóa học: " A pilot clinical trial testing mutant von HippelLindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma" doc
... RESEARC H Open Access A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic Renal Cell CarcinomaOsama E Rahma1, Ed Ashtar1, Ramy Ibrahim1, ... A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma. Journal of Translational Medicine 2010 8:8.Rahma et al. Journal ... were taken during the last vaccination visit forevery patient except patient 3 whom the last available T regs sample was during vaccination 5.Rahma et al. Journal of Translational Medicine 2010,...
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Báo cáo hóa học: " Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100derived epitope peptide " pot
... Tochigi, Japan), and Ms Setsuko Nakayama, Ms Asuka Asami and MsRuriko Miyake for their expert technical assistance (Department of Surgeryand Bioengineering, Advanced Clinical Research Center, Institute ... gp100 peptide to treat patients wi th metastatic melanoma.Methods: The phase I clinical protocol to test a HLA -A* 2402 gp100 peptide- based cancer vaccine was designed toevaluate safety as the ... Diagnostics, St. Louis, MO). A colon adenocarcinoma cell line, HT29 (HLA -A1 / A2 4) purchased from American Type Culture Coll ection(ATCC; Manassas, VA), and melanoma cell lines, 888mel (HLA -A1 /A2 4)...
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báo cáo hóa học: "Effect of auditory feedback differs according to side of hemiparesis: a comparative pilot study" pdf
... ischemic, Haem = haemorrhagic, Apraxia(+) = mild, Apraxia(++) = interferes with ADL, Aphasia score according to the Boston Diagnostic Aphasia Examination.Journal of NeuroEngineering and Rehabilitation ... tested;simple and spatial. In the case of the simple feedback, thevolume increased as the hand approached the target. Forthe spatial feedback, as well as increasing volume withproximity to the target, ... Box and Block(p = 0.25) or Barthel Index (p > 0.99).Symptoms such as aphasia, apraxia and neglect were alsonoted (Table 1). Aphasia was scored according to the Bos-ton Diagnostic Aphasia...
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báo cáo hóa học:" Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin" docx
... purposes)Journal of Translational MedicineOpen AccessResearchLentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatinSi ... ACTTCAGCGAGACCG-3';ABCC2 reverse: 5'-CCAGCCAGTTCAGGGTTT-3'; ACTBforward: 5'-CACCCAGCACAATGAAGAT-3'; ACTBreverse: 5'-CA AATAAAGCCATGCCAAT-3'. Cycling condi-tions ... overexpressing MRP2 by genetransfection [8]. The increased level of ABCC2 mRNA in some human carcinoma cell lines was associated with rel-ative cisplatin resistance owing to reducing intracellularaccumulation...
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báo cáo hóa học:" Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients" potx
... cytoplasmic staining.Immunoreactivity was assessed on a continuous scalewith values ranging from undetectable levels (0%) tohomogenous staining (100%) of invasive melanomacells.Measuring IGFBP-3 ... Translational MedicineOpen AccessResearchAssessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patientsJessie Z Yu1, Melanie A Warycha1, ... Buttarelli M, Cazzaniga M, Franchi D, Cassano E,Omodei U: A two-by-two factorial trial comparing oral withtransdermal estrogen therapy and fenretinide with placeboon breast cancer biomarkers....
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Báo cáo hóa học: " Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer" ppt
... EOC was assessedusing siRNA-mediated silencing of RBM3 in A2 780 cells followed by cell viability assay and cell cycle analysis.Results: Increased RBM3 mRNA expression was associated with a prolonged ... Uhlen M, Bjorling E, Agaton C, Szigyarto CA, Amini B, Andersen E,Andersson AC, Angelidou P, Asplund A, Asplund C, et al: A human proteinatlas for normal and cancer tissues based on antibody proteomics. ... protocols, as well as to guide the development and application of newtargeted therapies.Since its inception over 40 years ago, the platinum-based agent cisplatin has had a major impact on cancer therapy, ...
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báo cáo hóa học: " Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in dyspepsia: A six-country study" pptx
... lujszasz.1bel@semmelweis-miskolc.hu; Jonas Carlsson - jonas.carlsson@astrazeneca.com; Katarina Halling - katarina.halling@astrazeneca.com; Ingela K Wiklund - ingela.k.wiklund@gsk.com* Corresponding author AbstractBackground: ... relia-bility was acceptable in the Indigestion and Constipationdomains in most language versions. However, reliabilitywas lower in the Abdominal pain domains in all countriesassessed. As with ... generally low internal consistency in the Abdominalpain domain probably reflects the difficulty of measuringthis often fluctuating symptom, as well as the fact that theGSRS Abdominal pain domain...
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báo cáo hóa học: "Effect of obesity and low back pain on spinal mobility: a cross sectional study in women" pptx
... study, participated in data collection and analysis, andmanuscript writing; FM participated in data analysis, statistical analysis andmanuscript writing; FZ participated in the definition of ... and functional status in patients with spine disease. Spine 2002,27:306-312.2. Hangai M, Kaneoka K, Kuno S, Hinotsu S, Sakane M, Mamizuka N, Sakai S,Ochiai N: Factors associated with lumbar ... mobility at bothpelvic and thoracic level; a static postural adaptation with an increased anterior pelvic tilt. Obesity with cLBP isassociated with an increased lumbar lordosis. In lateral bending,...
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Báo cáo khoa học: Molecular characterization of recombinant mouse adenosine kinase and evaluation as a target for protein phosphorylation potx
... NY;6Intra-Cellular Therapies Inc., New York, NY;7Veterans Administration Medical Center, Dallas, TX, USAThe regulation of adenosine kinase (AK) activity has thepotential to control intracellular ... E-mail: james.bibb@utsouthwestern.eduAbbreviations: AK, adenosine kinase; Ado, adenosine; hAK, humanadenosine kinase; mAK, mouse adenosine kinase.Note: Nucleotide sequence data for the long and ... of human adenosinekinase cDNA: sequence similarity to microbial ribokinases andfructokinases. Proc. Natl Acad. Sci. USA 93, 1 232–1237.9. Latini,S.&Pedata,F.(2001)Adenosineinthecentralnervoussystem:...
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Báo cáo khoa học: Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon a-induced early antiviral signalling pdf
... maximal pathwayactivation and an increase in signal amplitude [3,4].Furthermore, alterations in the activity of a kinase orphosphatase may affect the speed of signalling pathwayactivation. However, ... isthe JAK ⁄ STAT pathway. The Janus kinases JAK1and tyrosine kinase 2 (TYK2) are activated in responseto ligand binding to the receptor, and these kinasesphosphorylate signal transducers and activators ... 10793) as primary antibody and anti-rabbitAlexa Fluor 680 (Invitrogen) as secondary antibody, andanalysed by flow cytometry using a FACSCalibur (BectonDickinson, Franklin Lakes, NJ, USA). As a control,...
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