báo cáo hóa học:" Correlation between expression of p53, p21

báo cáo hóa học:" Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma" docx

... Translational Medicine Open Access Research Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma Mei-Fang Zhang 1,2 , ... immunohistochemistry and examined the expression of the 3 proteins in 7 pairs of HCC tissues and the adjacent hepatic tissues by using western...

Ngày tải lên : 18/06/2014, 15:20

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Báo cáo khoa học: Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis potx

... site of action of these two proteins is the rate-limiting step in steroidogenesis [6]. Fatty acyl-CoAs bind to the acyl-CoA-binding protein, which can bind and may thereby activate PBR. This interaction ... acyl-CoA-binding protein known also as DBI (diazepam-binding inhibitor) is expressed at high concentrations in steroidogenic cells [26,27] and interacts with the PBR in the...

Ngày tải lên : 16/03/2014, 18:20

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Báo cáo hóa học: " Characterizing the burden of premature ejaculation from a patient and partner perspective: a multi-country qualitative analysis" docx

... Germany, and Poland and (2) to cognitively debrief males with PE and female partners of males with PE about their understanding of the recently developed single item measures of four dimensions of ... they experience during sexual intercourse, and this was directly related to the ability of bringing their partners to climax during vaginal intercourse. The women reported...

Ngày tải lên : 18/06/2014, 22:20

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Báo cáo khoa học: Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate kinase potx

... locations and interactions of the adenine and ribose rings in the C domain are very similar in all cases. The occupation and interactions of the nucleo- tide phosphate chain, however, are strikingly ... interplay and its role in both protein stability and function. In order to understand how the two substrates affect domain interplay and thereby induce the hinge-bendin...

Ngày tải lên : 16/03/2014, 18:20

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Báo cáo khoa học: "Correlation between ROUGE and Human Evaluation of Extractive Meeting Summaries" pptx

... evaluation in meetings. In this paper we investigate the correlation between ROUGE and human evaluation of extractive meeting summaries and focus on two issues speciﬁc to the meeting domain: disﬂuencies ... measure in maximum marginal relevance for meeting summarization. In ICASSP. X. Zhu and G. Penn. 2005. Evaluation of sentence selection for speech summarization....

Ngày tải lên : 17/03/2014, 02:20

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Báo cáo khoa học: Correlation between functional and structural changes of reduced and oxidized trout hemoglobins I and IV at different pHs doc

... in a reaction mixture containing 0.9 UÆmL )1 xanthine oxidase, 40 lgÆmL )1 of hemoprotein and 150 lmolÆL )1 lucigenin in 1 mL of the chosen buffer. The reaction was started by the injection of ... sensitive to the interactions between the heme and the surrounding globin, being in uenced by the attached ligand and thereby by the spin state of the iron atom [11]. According...

Ngày tải lên : 23/03/2014, 12:20

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báo cáo hóa học:" The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer" docx

... con- sensus. In tumor and normal epithelium, the expression of IDO and Bin1 was interpreted for immunoreactivity using the 0–4 semi-quantitative system of Gastl [37] for both the intensity of staining and ... epithelium. In primary colon cancer, the strong expression of IDO existed in 9/71 cases (12.7%), while the strong expression of Bin1 existed in 33/71 case...

Ngày tải lên : 18/06/2014, 15:20

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Báo cáo hóa học: "Microrna profiling analysis of differences between the melanoma of young adults and older adults" pot

... proteins (cartilage oligomeric matrix protein, COMP) [56]. The upregulation of miR-let-7b in the adult co mpared to the pediatric and young adult group is intriguing, in view of the finding of ... cytokine production, cell proliferation and induction of anti- apoptotic proteins as a result of the expression of an active IKKbeta pathway. It remains to be evaluated an...

Ngày tải lên : 18/06/2014, 16:20

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Báo cáo hóa học: " Correlation of pharmacodynamic activity, pharmacokinetics, and anti-product antibody responses to anti-IL-21R antibody therapeutics following IV administration to cynomolgus monkeys'''' pot

... ability of recombinant human IL-21 (rhuIL-21) to induce expression of interleukin-2 receptor alpha (IL- 2RA), IL-21R, perforin (PRF1), granzyme B (GZMB), and/ or interleukin 6 (IL-6) in cynomolgus ... in target binding affinity in vitro translated into an improved PK-PD profile in primates for Ab-02. Prior to conducting the in vivo PD study of anti-IL-21R antibodies in cy...

Ngày tải lên : 18/06/2014, 16:20

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Báo cáo hóa học: "IThe tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker" potx

... promote intestinal injury while inhibiting intestinal repair. Moreover, epithelial TLR signaling, acting in concert wit h TLR signaling by leukocytes, participates in the development of intestinal ... immunostaining in human colon tissues. 7a CD68 immunostaining in healthy tissues (A), ulcerative colitis (B), adenomas (C) and adenocarcinomas (D) shows a growing expression of...

Ngày tải lên : 18/06/2014, 16:20

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