báo cáo hóa học:" Short-term cultured, interleukin-15 differentiated dendritic cells have potent immunostimulatory properties" ppt

... purposes) Journal of Translational Medicine Open Access Research Short-term cultured, interleukin-15 differentiated dendritic cells have potent immunostimulatory properties Sébastien Anguille* 1,2 , Evelien ... study. Dendritic cell differentiation IL-4 differentiated dendritic cells (IL-4 DCs) GM-CSF 800 IU/mL Gentaur, Brussels, Belgium IL-4 20 ng/mL R&D Systems...

Ngày tải lên: 18/06/2014, 15:20

... therapy. Introduction Dendritic cells (DC) are key players in both innate and adaptive immune responses. They are potent antigen pre- senting cells that recognize, process, and present antigens to T -cells in ... generation of dendritic cells. J Immunol Methods 2005, 298:61-72. 11. Albert ML, Jegathesan M, Darnell RB: Dendritic cell maturation is required for the cross-tolerizat...

Ngày tải lên: 18/06/2014, 16:20

... non-healing edge fibroblasts. Cells from the wound-base (location A) migrate faster than non-healing edge cells (location B). Thus, cells from distinct locations within the wound have distinct migration ... morphological studies, previous investi- gators have successfully performed a variety of assays on cultured cells from venous ulcers[21,23]. Other investiga- tors have evalua...

Ngày tải lên: 18/06/2014, 15:20

... humans than originally thought, expressed not only in germinal cells and in a variety of somatic tissues, but also in neoplastic cells of unrelated histological ori- gin. For this reason, the ... in neoplastic cells from patients with multiple myeloma and ovarian carcinoma. These data all indicate that Sp17 is widely distributed in humans, expressed not only in germinal cells and in a...

Ngày tải lên: 18/06/2014, 15:20

... interaction between bone marrow derived progenitor cells (hemato- poetic progenitor cells, HPCs) and microvascular endothelial cells in bone marrow. Endothelial cells appear to regulate the trafficking ... circulating cells, including precursor cells, in postnatal neovascularization have presented novel therapeutic opportunities. Studied applications of endothelial-lineage cell th...

Ngày tải lên: 18/06/2014, 15:20

... cascades [27]. In particular, studies on liver tumor promotion have shown that dioxin-induced AHR activation mediates clonal expansion of initiated cells by inhibiting apoptosis and bypassing AHR-dependent ... with progression of HCV-related lesions to HCC. Competing interests The authors declare that they have no competing interests. Significant pathways at the nominal 0.001 level of t...

Ngày tải lên: 18/06/2014, 15:20

... tumor cells ID8 cells were exposed to Doxil at 0, 0.1, 0.3 or 1 μg/ml concentrations for 6 hours. The cells were washed twice with PBS, and cultured in drug-free media for another 42 hours. ID8 cells ... assay ID8-E6E7 cells were used as targets in a colorimetric non- radioactive cytotoxicity assay measuring LDH (Promega). Target cells (12 × 10 3 cells/ well) were coincubated wit...

Ngày tải lên: 18/06/2014, 15:20

... TGN1412 to rhesus T cells had been demonstrated prior to clinical testing [16], but biological activity of TGN1412 on rhesus cells had not been extensively explored. In contrast, we have shown that ... sensitive assays than have been reported with a known immunotoxic ago- nist antibody. In addition we have demonstrated that this anti-IL21R antibody binds to cynomolgus monkey blood...

Ngày tải lên: 18/06/2014, 16:20

... and invasion [14]. In previous in vitro studies, we have shown that interac- tion of IBC cells with human monocytes augments inva- sion of IBC cells through increased ECM degradation, events correlated ... increase in cav-1 expression in the IBC cells [15]. More recently, we have co-localized active CTSB and uPA with cav-1 in caveolar fractions of SUM149 IBC cells (unpublished dat...

Ngày tải lên: 18/06/2014, 16:20

... siblings. Children with any chronic condition have twice the risk of developing mental health disorders of healthy children, and three times the risk if they have an accompanying disability[4]. The ... of asthmatic children- have poor QOL especially in their emotional domain affecting their social life[10]. Regarding parents of cancer children, it was found that they have high levels...

Ngày tải lên: 18/06/2014, 19:20